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1. Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure Pattern - Mayo Clinic

   These subjects have an established diagnosis of focal or generalized epilepsy with a documented history of predictable seizure episodes. This is an in-patient ...

2. A Study of Pre-Conditioning Prior to Surgery to Improve Functional and Clinical Outcomes in Patients with Aortic Stenosis

   The purpose of this study is to evaluate whether simple cardiac exercise interventions to improve physical performance before transcatheter aortic valve ...

3. Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

4. A Study to Remodel the Mitral Annulus following Robotic-Assisted Surgical Mitral Valve Repair - Mayo Clinic

   The purpose of this study is to investigate post-operative changes in cardiac structure and function for patients with mitral regurgitation to define heart ...

5. Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery - Mayo Clinic

   What is the incidence and etiology of bone overgrowth in protein versus other bone graft? Participation eligibility. Participant eligibility includes age, ...

6. Phase 3 Study of PDS0101 and Pembrolizumab in HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma - Mayo Clinic

   pembrolizumab monotherapy as first-line treatment in patients with unresectable recurrent or metastatic HPV16-positive HNSCC expressing programmed cell death ...

7. Randomized Study to Assess the Safety, Pharmacokinetics/Dynamics of DS-1040b in Subjects With Acute Submassive Pulmonary Embolism - Mayo Clinic

   About this study. This is a Phase 1b, double-blind (Principal Investigators, study subjects, Sponsor, Academic Research Organization ARO and Clinical ...

8. Post-Operative Mobility after Operative Fixation of Geriatric Distal Femur Fractures - Mayo Clinic

   About this study. The purpose of this study is determine which fixation construct affords better mobility and return to functional independence for patients ...

9. Veliparib with or without Carboplatin in Treating Patients with Stage III or Stage IV Breast Cancer - Mayo Clinic

   Veliparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin, work in ...

10. A Study to Evaluate the Efficacy and Safety of Lenalidomide as Maintenance Therapy for Patients With B-Cell Chronic Lymphocytic Leukemia (CLL) Following Second Line Therapy - Mayo Clinic

    The purpose of this study is to determine if lenalidomide (Revlimid®) is safe and effective as a maintenance therapy at improving further the quality of the ...