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1. Transcatheter Aortic Valve Replacement for Transcatheter Aortic Valve Failure - Mayo Clinic

   The purpose of this study is to generate clinical evidence on valve safety and performance in subjects treated by redo TAVR. Participation eligibility.

2. Long-Term Outcome Following the Treatment of Pediatric Scoliosis - Mayo Clinic

   Evaluate the long-term outcomes following operative and nonoperative treatment of childhood scoliosis. Participation eligibility. Participant eligibility ...

3. Randomized Controlled Trial of Tranexamic Acid in Total Knee Arthroplasty: Intravenous vs. Topical - Mayo Clinic

   Tranexamic acid is a synthetic drug that has been shown to reduce blood drain output and the need for blood transfusions in both its topical and intravenous ...

4. Outcomes and Quality of Life Following Heller’s Myotomy for Achalasia With a Sigmoid Esophagus - Mayo Clinic

   The purpose of this study is to assess symptoms and quality of life in patients following Heller's cardiomyotomy for achalasia in the context of a sigmoid ...

5. A Study of Whole Exome Sequencing and Other Omics in Human Disease - Mayo Clinic

   NGS is a procedure that looks at all of your genes (the genetic material you have inherited from your parents). In this study, we want to collect detailed ...

6. Patient Centered Approaches to Gene Editing Research Study - Mayo Clinic

   The purpose of this study is to elicit clinicians' and scientists' views, ethical concerns, clinical aspirations and governance needs regarding prenatal gene ...

7. A Phase 1-2 Multi-Center Study Evaluating Axicabtagene Ciloleucel in Subjects With Refractory Aggressive Non-Hodgkin Lymphoma (ZUMA-1) - Mayo Clinic

   This is a single arm, open-label, multi-center, phase 1/2 study, to determine the safety and efficacy of KTE-C19, an autologous anti-CD19 chimeric antigen ...

8. A Study to Support the Use of Digital Tools to Evaluate a Patient's Range of Motion - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

9. A Study to Evaluate the Effect of Olorinab on Gastrointestinal Transit in Patients with Irritable Bowel Syndrome - Mayo Clinic

   The purpose of this study is to evaluate gastric, small-bowel, and colonic transit in subjects with IBS-C and IBS-D treated with multiple (three times daily) ...

10. A Study to Assess the Natural History and Routine Clinical Management of Congenital Disorders of Glycosylation

    The purpose of this study is to collect natural history and treatment-related data of patients diagnosed with congenital disorders of glycosylation.