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  1. A Study of Momelotinib Versus Danazol in Symptomatic and Anemic Myelofibrosis Patients - Mayo Clinic

    Subjects randomized to receive DAN who are receiving clinical benefit at the end of Week 24 may choose to continue DAN therapy up to Week 48. The comparator ...

  2. A Study of SC-006 in Subjects With Advanced Cancer - Mayo Clinic

    About this study. This is a multicenter, open-label, Phase 1 study in participants with colorectal cancer (CRC), and consists of Part A (dose regimen ...

  3. A Study to Assess the Effectiveness and Safety of Apremilast in Pediatric Patients (6 through 17 years old) with Moderate-to-Severe Plaque Psoriasis - Mayo Clinic

    The primary purpose of this study is to evaluate the clinical effectiveness of apremilast compared with placebo in children and adolescents (ages 6 through 17 ...

  4. Efficacy and Safety Trial of Apatinib Plus Best Supportive Care Compared to Placebo Plus Best Supportive Care in Patients With Gastric Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. A Study to Evaluate Firstline Pembrolizumab Alone or in Combination with Pemetrexed and Carboplatin in Induction/Maintenance or Postprogression in Treating Patients with Stage IV Non-squamous Non-small Cell Lung Cancer - Mayo Clinic

    Drugs used in chemotherapy, such as pemetrexed and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by ...

  6. Prostate cancer - Doctors and departments - Mayo Clinic

    Learn about detection, diagnostic approaches, treatment options and advances for prostate cancer, including robotic prostatectomy and current research.

  7. Androgen Deprivation To Enrich PSMA Expression And Improve Sensitivity Of Staging PSMA PET/C - Mayo Clinic

    The purpose of this study is for the comparison of SUVmax and SUVmean values of the dominate primary prostate lesion between pre and post ADT imaging using ...

  8. Trametinib, Combination Chemotherapy, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed by Surgery - Mayo Clinic

    Trametinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as carboplatin and ...

  9. A Randomized Study of Olaparib or Placebo in Patients With Surgically Removed Pancreatic Cancer Who Have a BRCA1, BRCA2 or PALB2 Mutation, The APOLLO Trial - Mayo Clinic

    Olaparib is an inhibitor of PARP, an enzyme that helps repair deoxyribonucleic acid (DNA) when it becomes damaged. Blocking PARP may help keep tumor cells from ...

  10. Drugs and Supplements that Start with F - Mayo Clinic

    Explore a comprehensive list of prescription and over-the-counter medications starting with the letter “F” to learn about drug side effects, proper use and ...