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  1. A Study to Evaluate the Safety, Tolerability, Effectiveness, Biological Activity, and Drug/Body Interactions of MYK-461 in Patients with Symptomatic Enlargement of the Heart and Obstruction of Left Ventricle Outflow - Mayo Clinic

    A Study to Evaluate the Safety, Tolerability, Effectiveness, Biological Activity, and Drug/Body Interactions of MYK-461 in Patients with Symptomatic Enlargement ...

  2. A Study to Assess the Safety, Tolerability and Effectiveness of LJN452 for Treating Patients who have Primary Biliary Cholangitis - Mayo Clinic

    The purpose of this study is to assess the safety, tolerability and effectiveness of LJN452 for the treatment of patients who have primary biliary cholangitis.

  3. A Study to Evaluate the Safety, Tolerability, and Clinical Benefit of AK002 in Adult Patients with Mast Cell Gastritis and/or Gastroenteritis

    About this study. The purpose of this study is to evaluate the safety and tolerability of AK002 in patients with mast cell gastritis and/or gastroenteritis, ...

  4. NEURO-TTRansform: A Study to Evaluate the Efficacy and Safety of AKCEA-TTR-LRx in Participants With Hereditary Transthyretin-Mediated Amyloid Polyneuropathy - Mayo Clinic

    Neuropathy Symptom and Change Score (NSC); Physical component summary (PCS) score of 36-Item Short Form Survey (SF-36); Polyneuropathy disability (PND) score ...

  5. Escalating Dose Study in Subjects with Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia - Mayo Clinic

    Escalating Dose Study in Subjects with Relapsed or Refractory B Cell Non-Hodgkin Lymphoma, Chronic Lymphocytic Leukemia, and Waldenstrom's Macroglobulinemia.

  6. Infection Database of Mechanical Circulatory Assist Device Recipients - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  7. Siemens AcuNav Crystal ICE Catheter in Evaluation of Cardiac Anatomy and Physiology During Electrophysiology and Structural Heart Interventional Procedures - Mayo Clinic

    Siemens AcuNav Crystal ICE Catheter in Evaluation of Cardiac Anatomy and Physiology During Electrophysiology and Structural Heart Interventional Procedures.

  8. Phase 1b Safety Study of CMB305 in Patients With Locally Advanced, Relapsed, or Metastatic Cancer Expressing NY-ESO-1 - Mayo Clinic

    About this study. This is a Phase 1b, open label, multi-center study of CMB305 (sequentially administered LV305 [a dendritic cell-targeting viral vector ...

  9. Evaluation of the Zone-MPC Control Algorithm Integrated into the iAPS in Pregnant Patients with Type 1 Diabetes - Mayo Clinic

    The purpose of this research is to test the safety and effectiveness of the interoperable Artificial Pancreas System Smartphone App (iAPS) in managing blood ...

  10. S0931, Everolimus in Treating Patients With Kidney Cancer Who Have Undergone Surgery - Mayo Clinic

    About this study. RATIONALE: Everolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth or by blocking blood flow ...