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1. Ribociclib and Gemcitabine Hydrochloride in Treating Patients With Advanced or Metastatic Solid Tumors - Mayo Clinic

   Ribociclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as gemcitabine ...

2. A Study of the Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients with Aortic Stenosis - Mayo Clinic

   The purpose of this study is to establish the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Heart Valve in patients who have severe, ...

3. Prostate cancer - Doctors and departments - Mayo Clinic

   Learn about detection, diagnostic approaches, treatment options and advances for prostate cancer, including robotic prostatectomy and current research.

4. TAS-102 and Radiation Therapy in Treating Patients With Rectal Cancer That Is Locally Recurrent, Metastatic, or Cannot Be Removed by Surgery - Mayo Clinic

   About this study. This phase I trial studies the side effects and best dose of trifluridine/tipiracil hydrochloride combination agent TAS-102 (TAS-102) when ...

5. A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer - Mayo Clinic

   This is a randomized, open-label, three-arm, phase 3 study in men with biochemically recurrent prostate cancer and PSA doubling time ≤ 9 months at the time of ...

6. A Dose Ranging Phase IIa Study of 6 Hour Intravenous Dosages of CXL-1427 in Patients Hospitalized With Heart Failure - Mayo Clinic

   A randomized, double-blinded, placebo-controlled study of continuous 6-hour IV infusions of CXL-1427 in hospitalized patients with systolic heart failure.

7. Androgen Deprivation to Enrich PSMA Expression and Improve Sensitivity of Staging PSMA PET/C - Mayo Clinic

   The purpose of this study is for the comparison of SUVmax and SUVmean values of the dominate primary prostate lesion between pre and post ADT imaging using ...

8. A Study to Optimize Stroke Thrombolysis - Mayo Clinic

   Patients may also receive endovascular thrombectomy (ET) per usual care. Time of onset is defined as the last time the patient was last known to be well.

9. Sirolimus, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients At High Risk for Cholangiocarcinoma Recurrence After Liver Transplant or Surgery - Mayo Clinic

   Sirolimus may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as gemcitabine ...

10. A Dose Escalation and Confirmation Study of PT-112 in Advanced Solid Tumors in Combination With Avelumab - Mayo Clinic

    The Dose Confirmation Phase will consist of two additional cohorts in patients with non-small cell lung cancer or urothelial carcinoma who will be treated at or ...