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  1. Sorafenib Tosylate and Hypoxia-Activated Prodrug TH-302 in Treating Patients With Advanced Kidney Cancer or Liver Cancer That Cannot Be Removed By Surgery - Mayo Clinic

    About this study. RATIONALE: Sorafenib tosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth by blocking blood ...

  2. Effects of Aprepitant on Satiation, Gastric Volume, Gastric Accommodation and Gastric Emptying - Mayo Clinic

    This research study is being done to compare the effects of Aprepitant and placebo on fasting gastric volume, accommodation volume, satiation (fullness) and ...

  3. A Study to Evaluate the Effectiveness and Safety of Vibegron Administered Orally for 12 Weeks to Women with Irritable Bowel Syndrome - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of vibegron, a beta-3 adrenergic receptor (β3-AR) agonist, in the treatment of pain ...

  4. A Study to Evaluate Glucagon Ready to Use (RTU) in Subjects With Hyperinsulinemic Hypoglycemia After Bariatric Surgery - Mayo Clinic

    Subjects will be randomly assigned to either Glucagon RTU or Placebo for the duration of a 12-week Outpatient Stage. A follow-up safety assessment visit will ...

  5. Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP) - Mayo Clinic

    The primary objective of this study is to asssess the safety and tolerability of TPN-101 in patients with progressive supranuclear palsy (PSP). Participation ...

  7. A Study of ASP8273 versus Erlotinib or Gefitinib as First-Line Treatment for Patients with Stage IIIB/IV Non-Small Cell Lung Cancer - Mayo Clinic

    This study will also assess overall survival, overall response rate, progression free survival assessed by the investigator, disease control rate, duration of ...

  8. A Study of MBG453 in Combination With Azacitidine and Venetoclax in AML Patients Unfit for Chemotherapy - Mayo Clinic

    This trial will seek to extend the preliminary findings of efficacy of MBG453 in combination with hypomethylating agents (HMA) by evaluating MBG453 in ...

  9. Cardiovascular Medicine - Clinical trials - Mayo Clinic

    The purpose of this study is to describe the clinical impact of cardiac rehabilitation in patients who have undergone myectomy for hypertrophic cardiomyopathy.

  10. Cardiovascular Medicine - Clinical trials - Mayo Clinic

    The primary purpose of this study is to assess the feasibility of performing lung and kidney and lung ultrasound elastography among patients with critical ...