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1. A Study of Atezolizumab as Adjuvant Therapy in Participants With Renal Cell Carcinoma (RCC) at High Risk of Developing Metastasis Following Nephrectomy - Mayo Clinic

   This is a Phase III, multicenter, randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of atezolizumab versus placebo in ...

2. Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy - Mayo Clinic

   About this study. Pazopanib is FDA approved as a second line and beyond treatment for metastatic soft tissue sarcoma. There is a population of elderly and ...

3. A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Effect on Disease Progression of BIIB078 in Amyotrophic Lateral Sclerosis (ALS) Patients - Mayo Clinic

   The secondary objective is to evaluate the pharmacokinectics or movement of drug throughout the body (PK) of BIIB078 in participants with C9ORF72-ALS.

4. Ixazomib Citrate, Pomalidomide, Dexamethasone, and Stem Cell Transplantation in Treating Patients With Relapsed or Refractory Multiple Myeloma - Mayo Clinic

   Giving chemotherapy, such as pomalidomide and dexamethasone, before a stem cell transplant helps kill any cancer cells that are in the body and helps make room ...

5. Study to Evaluate the Efficacy and Safety of Gefapixant (MK-7264) in Adult Participants with Chronic Cough - Mayo Clinic

   The purpose of this study is to evaluate the sasfety and effectiveness of MK-7264 in reducing cough frequency as measured over a 24-hour period. Participation ...

6. A Study Evaluating the Effectiveness and Safety of Axicabtagene Ciloleucel in Subjects with High-Risk Large B-Cell Lymphoma - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

7. Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE) - Mayo Clinic

   About this study. The objectives of this study are to assess the effectiveness of NBI-921352 as adjunctive therapy on the frequency of countable motor ...

8. Cardiovascular Medicine - Clinical trials - Mayo Clinic

   Rochester, Minn. The purpose of this study is to elucidate the genetic basis of aBiMVP in hopes of determining novel mechanisms that underlie aBiMVP ...

9. A Study to Evaluate the Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALS - Mayo Clinic

   The purpose of this study is to evaluate whether prolonged oral levosimendan can preserve respiratory function more effectively than placebo, resulting in ...

10. A Study to Assess the Effectiveness, Safety, and Drug/Body Interactions of Rovalpituzumab for Third-Line and Later Treatment of Patients with Small Cell Lung Cancer that has Returned or is Resistant to Treatment - Mayo Clinic

    A Study to Assess the Effectiveness, Safety, and Drug/Body Interactions of Rovalpituzumab for Third-Line and Later Treatment of Patients with Small Cell Lung ...