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  1. MC200404, Safety and Immunogenicity of PolyPEPI1018 Vaccine in the Treatment of Late-stage Metastatic Colorectal Cancer - Mayo Clinic

    However, TAS-102 is FDA approved for treatment of metastatic colorectal cancer. The FDA has allowed the use of this combination in this research study.

  2. Combination Chemotherapy With or Without Trastuzumab in Treating Women With Breast Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. Intrathecally Administered Gene Therapy APB-102 in Rapidly Progressive ALS Patients with SOD1 Mutations - Mayo Clinic

    This is a Phase 1/2 open-label, multicenter study to evaluate the safety and tolerability and to explore the efficacy of gene therapy AMT-162 in Participants ...

  4. Study of Orally Administered AG-120 in Subjects with Advanced Hematologic Malignancies with an IDH1 Mutation - Mayo Clinic

    About this study. The purpose of this Phase I, multicenter study is to evaluate the safety, pharmacokinetics, pharmacodynamics and clinical activity of ...

  5. Probe-based Volumetric Laser Endomicroscopy (pVLE) of Endoscopic Mucosal Resection (EMR) Tissue in Patients With Barrett's Dysplasia - Mayo Clinic

    Probe-based Volumetric Laser Endomicroscopy (pVLE) of Endoscopic Mucosal Resection (EMR) Tissue in Patients With Barrett's Dysplasia · Overview · Participation ...

  6. A Study to Evaluate the Effectiveness and Safety of Vibegron Administered Orally for 12 Weeks to Women with Irritable Bowel Syndrome - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of vibegron, a beta-3 adrenergic receptor (β3-AR) agonist, in the treatment of pain ...

  7. A Study to Compare the Effectveness of Colon Capsule Endoscopy versus Computed Tomographic Colonography in Screening to Identify Colon Polyps - Mayo Clinic

    The purpose of this study is to compare the effectiveness of Colon Capsule Endoscopy versus Computed Tomographic Colonography for the screening of colon polyps ...

  8. Ixazomib Plus Pomalidomide and Dexamethasone in Treating Patients with Relapsed or Relapsed/Refractory Multiple Myeloma - Mayo Clinic

    Ixazomib may stop the growth of cancer by interfering with proteasomes (the protein breakdown mechanism in the cells). Pomalidomide and dexamethasone can modify ...

  9. Study to Determine How Cialis Effects the Renal Function in Response to Volume Expansion in Preclinical Diastolic Cardiomyopathy (Aim 3) - Mayo Clinic

    About this study. To determine the effect of 12 weeks of chronic PDEV inhibition with Tadalafil versus placebo on basal cardiorenal and humoral function and ...

  10. A Study to Evaluate Firstline Pembrolizumab Alone or in Combination with Pemetrexed and Carboplatin in Induction/Maintenance or Postprogression in Treating Patients with Stage IV Non-squamous Non-small Cell Lung Cancer - Mayo Clinic

    Drugs used in chemotherapy, such as pemetrexed and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by ...