By Mayo Clinic Staff

Dietitian's tip:

This Italian favorite has less fat and fewer calories but all of the taste. Using low-fat cheeses and extra-lean ground beef saves 100 calories and 10 grams of fat a serving.

Number of servings

Serves 12
  1. Weight management
  2. Diabetes meal plan
  3. DASH diet

Ingredients

  1. 1 pound extra-lean ground beef
  2. 1 onion, chopped
  3. 1 1/2 teaspoons dried basil
  4. 3/4 teaspoon dried oregano
  5. 3/4 teaspoon garlic powder
  6. 1 can (6 ounces) unsalted tomato paste
  7. 1 can (8 ounces) unsalted tomato sauce
  8. 3 1/2 cups water
  9. 3/4 pound uncooked lasagna noodles
  10. 1 cup low-fat cottage cheese
  11. 3 cups shredded low-fat mozzarella cheese

Directions

Heat the oven to 325 F. Lightly coat a 9-by-13-inch pan with cooking spray.

To make the sauce, in a large saucepan combine the ground beef and onion. Cook over medium heat until the beef is browned and onion is translucent. Drain well. Add the basil, oregano, garlic powder, tomato paste, tomato sauce and water. Stir to mix evenly. Bring to a boil. Then reduce heat and simmer for 10 minutes.

Put 1/2 cup of the sauce in the bottom of the prepared pan. Cover with a layer of uncooked lasagna noodles, 1/3 of the remaining sauce, 1/3 cup cottage cheese and 1 cup mozzarella cheese. Repeat until the ingredients are used up. Cover with aluminum foil and bake until the noodles are soft and the cheese is lightly browned, about 1 hour and 20 minutes.

Nutritional analysis per serving

Serving size: 1 piece

  • Total fat 11 g
  • Calories 300
  • Protein 19 g
  • Cholesterol 40 mg
  • Total carbohydrate 29 g
  • Dietary fiber 3 g
  • Monounsaturated fat 4 g
  • Saturated fat 5 g
  • Sodium 264 mg
  • Total sugars 5 g
  • Trans fat Trace
  • Added sugars 0 g
  • Polyunsaturated fat 1 g
  • Potassium 383 mg
  • Calcium 177 mg
  • Magnesium 18 mg
  • Vitamin D 3 IU
  • Iron 3 mg
April 08, 2026