Side Effects

Drug information provided by: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Swelling, redness, or pain at the injection site

Less common

  1. Changes in skin color
  2. dry, red, hot, or irritated skin
  3. joint pain
  4. muscle pain
  5. pain
  6. redness, burning sensation, or pain under the skin usually in the injection site
  7. swelling of the foot or leg
  8. tenderness


  1. Agitation
  2. anxiety
  3. back, leg, or stomach pains
  4. black, tarry stools
  5. bleeding gums
  6. bloating or swelling of the face, arms, hands, lower legs, or feet
  7. blood in the urine
  8. bloody, black, or tarry stools
  9. blue lips, fingernails, or skin
  10. blurred vision
  11. bone pain
  12. burning, tingling, numbness, or pain in the hands, arms, feet, or legs
  13. chest pain or discomfort
  14. chest pain, possibly moving to the left arm, neck, or shoulder
  15. chills
  16. coma
  17. confusion
  18. constipation
  19. convulsions or seizures
  20. cough or hoarseness
  21. darkened urine
  22. decreased urine output
  23. difficult, fast, or labored breathing
  24. difficult or painful urination
  25. difficulty with moving
  26. difficulty with swallowing
  27. dizziness
  28. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  29. drowsiness
  30. extremely shallow or slow breathing
  31. fainting
  32. fast, slow, irregular, pounding, or racing heartbeat or pulse
  33. feeling of warmth or heat
  34. flushing or redness of the skin, especially on the face and neck
  35. general body swelling
  36. general tiredness and weakness
  37. hallucinations
  38. headache
  39. high fever
  40. hives
  41. inability to speak
  42. increased thirst
  43. indigestion
  44. irritability
  45. itching
  46. light-colored stools
  47. loss of appetite
  48. loss of bladder control
  49. loss of consciousness
  50. loss of strength or energy
  51. lower back or side pain
  52. muscle pain or cramps
  53. muscle stiffness or weakness
  54. nausea or vomiting
  55. no blood pressure or pulse
  56. nosebleeds
  57. not breathing
  58. pain in the joints
  59. pains in the stomach, side, or abdomen, possibly radiating to the back
  60. pale skin
  61. problems with bleeding or clotting
  62. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  63. rapid weight gain
  64. redness, burning sensation, or pain in the vagina
  65. sensation of pins and needles
  66. severe bloody diarrhea
  67. severe or sudden headache
  68. shakiness in the legs, arms, hands, or feet
  69. shortness of breath
  70. skin rash
  71. skin rash with red patches
  72. slurred speech
  73. sore throat
  74. sores on the skin
  75. sores, ulcers, or white spots on the lips or in the mouth
  76. stabbing pain
  77. stiff neck
  78. stopping of the heart
  79. sweating
  80. swelling of the face, ankles, or hands
  81. swollen glands
  82. temporary blindness
  83. tightness in the chest
  84. tingling of the hands or feet
  85. total body jerking
  86. trembling or shaking of the hands or feet
  87. troubled breathing
  88. unconsciousness
  89. unexplained bleeding or bruising
  90. unusual tiredness or weakness
  91. unusual weight gain or loss
  92. upper right abdominal or stomach pain
  93. vomiting
  94. vomiting of blood or material that looks like coffee grounds
  95. weakness in the arm or leg on one side of the body, sudden and severe
  96. wheezing
  97. worsening of the underlying disease
  98. yellowing of the eyes or skin

Incidence not known

  1. Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:


  1. Acid or sour stomach
  2. ankle, knee, or great toe joint pain
  3. belching
  4. cold sweats
  5. cool, pale skin
  6. cramps in the legs
  7. depression
  8. excessive muscle tone
  9. heartburn
  10. hives or welts
  11. increased hunger
  12. itching of the vagina or genital area
  13. joint stiffness or swelling
  14. lower back or side pain
  15. muscle tension or tightness
  16. nightmares
  17. pain during sexual intercourse
  18. redness of the skin
  19. shakiness
  20. sleeplessness
  21. stomach discomfort, upset, or pain
  22. sweating
  23. swelling or inflammation of the mouth
  24. thick, white vaginal discharge with no odor or with a mild odor
  25. trouble sleeping
  26. unable to sleep
  27. white patches in the mouth, tongue, or throat

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.