Description and Brand Names

Drug information provided by: Merative, Micromedex®

US Brand Name

  1. Fusilev
  2. Khapzory


Levoleucovorin injection is used as a rescue treatment after high-dose methotrexate treatment in patients with osteosarcoma (bone cancer). It is also used to lessen the toxic effects of folic acid blocker overdose or methotrexate in patients who cannot eliminate this drug properly from their bodies. Levoleucovorin injection is also used together with fluorouracil to treat metastatic (cancer that has spread) colon or rectal cancer.

This medicine is to be given by or under the direct supervision of your doctor.

This product is available in the following dosage forms:

  • Powder for Solution
  • Solution