Description and Brand Names

Drug information provided by: Merative, Micromedex®

US Brand Name

  1. Supprelin LA
  2. Vantas


Histrelin is a synthetic (man-made) hormone that is similar to a natural hormone that is produced in the brain. This medicine works in the brain to reduce the blood levels of sex hormones, such as testosterone and estrogen. It is inserted just beneath the skin of the upper arm where it releases small amounts of histrelin in the body every day for 12 months.

Histrelin (Vantas®) is used to treat advanced prostate cancer in adults. It will reduce the level of testosterone, a male hormone, in the blood. Testosterone makes most prostate cancers grow. Histrelin is not a cure for prostate cancer, but it may help relieve the symptoms.

Histrelin (Supprelin® LA) is used to treat central precocious puberty (CPP) in children. CPP is a condition wherein puberty begins at an unusually early age. This usually means puberty occurs before 8 years of age in girls and before 9 years of age in boys.

This medicine is to be given only by or under the direct supervision of a trained healthcare professional.

This product is available in the following dosage forms:

  • Implant