Description and Brand Names

Drug information provided by: Micromedex

US Brand Name

  1. Duragesic
  2. Ionsys

Canadian Brand Name

  1. Duragesic Mat


The fentanyl skin patch (transdermal) is used to treat severe pain, including acute pain following surgery. Ionsys® is applied in a hospital setting after surgery for the short-term management of acute pain. Duragesic® is used for severe chronic pain when around-the-clock pain relief is needed for a long period of time. Fentanyl is a strong narcotic analgesic (pain medicine). It acts on the central nervous system (CNS) to relieve pain.

The Duragesic® skin patch should not be used if you need pain medicine for just a short time, such as after dental surgery or tonsil surgery. Do not use the patch for mild pain or pain that occurs only once in a while.

The Ionsys® skin patch is applied by your healthcare provider to the upper outer arm or chest in the hospital.

When a narcotic medicine is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics if needed. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly, but the adverse effects can usually be prevented by gradually reducing the dose.

This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

  • Patch, Extended Release
  • Patch, Device Assisted