Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Agitation
  2. anxiety
  3. bladder pain
  4. bloody or cloudy urine
  5. crying
  6. delusions of persecution, mistrust, suspiciousness, or combativeness
  7. difficult, burning, or painful urination
  8. false or unusual sense of well-being
  9. feeling of unreality
  10. frequent urge to urinate
  11. lower back or side pain
  12. mental depression
  13. nervousness
  14. quick to react or overreact emotionally
  15. rapidly changing moods
  16. sense of detachment from self or body

Less common

  1. Chills
  2. cough
  3. fever
  4. hoarseness


  1. Seeing, hearing, or feeling things that are not there
  2. severe mental changes

Incidence not known

  1. Blistering, peeling, loosening of the skin
  2. blurred vision
  3. chest pain or discomfort
  4. confusion
  5. dark urine
  6. diarrhea
  7. difficulty breathing
  8. dizziness
  9. fainting
  10. fast, irregular, pounding, or racing heartbeat or pulse
  11. headache
  12. hives, itching, skin rash
  13. joint or muscle pain
  14. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or genitals
  15. mood swings
  16. muscle cramps, pain, stiffness, or spasms
  17. nausea
  18. overactive reflexes
  19. pain or discomfort in the arms, jaw, back, or neck
  20. paleness or cold feeling in the fingertips and toes
  21. pounding in the ears
  22. red skin lesions, often with a purple center
  23. red, irritated eyes
  24. restlessness
  25. shakiness in the legs, arms, hands, or feet
  26. shivering
  27. slow or fast heartbeat
  28. sore throat
  29. sores, ulcers, or white spots in the mouth or on the lips
  30. sweating
  31. swelling of the feet or lower legs
  32. talking or acting with excitement you cannot control
  33. tingling or pain in the fingers or toes when exposed to cold temperatures
  34. trouble sleeping
  35. twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  36. uncontrolled vocal outbursts or tics (uncontrolled repeated body movements)
  37. unusual tiredness or weakness
  38. vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Aggressive
  2. agitation
  3. angry
  4. blurred vision
  5. change in consciousness
  6. chest pain or discomfort
  7. confusion
  8. dark urine
  9. diarrhea
  10. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  11. extremely high fever or body temperature
  12. fainting
  13. fast breathing
  14. fast, slow, or irregular heartbeat
  15. headache
  16. inability to speak
  17. loss of bladder control
  18. loss of consciousness
  19. muscle cramps, spasms, jerking, pain, or stiffness
  20. nausea
  21. nervousness
  22. overactive reflexes
  23. pain or discomfort in the arms, jaw, back, or neck
  24. pale, clammy skin
  25. palpitations
  26. panic states
  27. physical attempt to injure
  28. poor coordination
  29. pounding in the ears
  30. restlessness
  31. seeing, hearing, or feeling things that are not there
  32. seizures
  33. shakiness in the legs, arms, hands, or feet
  34. shivering
  35. slurred speech
  36. stomach cramps
  37. sudden loss of consciousness
  38. sweating
  39. swelling of the feet or lower legs
  40. talking or acting with excitement you cannot control
  41. temporary blindness
  42. thirst
  43. trembling or shaking of the hands or feet
  44. unusual tiredness or weakness
  45. violent actions
  46. vomiting
  47. weakness in the arm or leg on one side of the body, sudden and severe

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Dry mouth
  2. loss of appetite
  3. stomach ache
  4. voice changes
  5. weight loss

Less common

  1. Belching
  2. heartburn
  3. indigestion
  4. stomach discomfort, upset, or pain

Incidence not known

  1. Constipation
  2. decreased interest in sexual intercourse
  3. difficulty having a bowel movement
  4. inability to have or keep an erection
  5. loss in sexual ability, desire, drive, or performance
  6. redness of the skin
  7. thinning or loss of hair
  8. unpleasant taste

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

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