Liver fibrosis

Stages

Healthcare professionals often describe liver fibrosis in stages based on how much scar tissue is present in the liver. These stages help estimate how severe the scarring is and how likely the disease is to worsen over time.

Liver fibrosis is commonly described using stages from F0 to F4.

• F0 means there is no liver scarring.
• F1 means mild scarring is present but the liver structure is mostly preserved.
• F2 means moderate scarring has begun to occur within the liver.
• F3 means advanced scarring that affects larger areas of the liver and disrupts blood flow.
• F4 means cirrhosis, the most severe stage, in which extensive scarring causes lasting damage to the liver.