Hypereosinophilic syndrome care at Mayo Clinic

Your Mayo Clinic care team

Hypereosinophilic syndrome (HES) can affect many parts of your body. Mayo Clinic's HES care team includes specialists in allergic diseases, skin diseases, digestive disorders, heart disease, brain and nervous system disorders, blood disorders, and cancer.

Having all of this subspecialized expertise in a single place, focused on you, means that you're not just getting one opinion. Care is discussed among the team, and appointments are scheduled to be well coordinated. Highly specialized HES experts are all working together to determine what's best for you.

Advanced diagnosis and treatment

HES is a diverse and complex syndrome. Extensive testing is often needed to refine a diagnosis and assess potential damage to organs.

At Mayo Clinic, a detailed plan for appointments, tests and procedures helps make the best use of your time. Mayo Clinic technicians run all tests and labs themselves, shortening the time for test results. Mayo's collaborative approach means diagnosis and care insights can happen in a timely manner.

Expertise and rankings

HES is a rare disorder, so it can be difficult to find a healthcare professional who has much experience in treating it. Doctors at Mayo Clinic see many people with HES each year.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

June 27, 2025

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