Stages By Mayo Clinic Staff During or after testing for heart failure, your healthcare professional may tell you the stage of disease. Staging helps determine the most appropriate treatment. There are two main ways to determine the stage of heart failure: New York Heart Association (NYHA) classification This system groups heart failure into four categories by number. You may see Roman numerals used for these category names. Class 1 heart failure. There are no heart failure symptoms. Class 2 heart failure. Everyday activities can be done without difficulty. But exertion causes shortness of breath or fatigue. Class 3 heart failure. It's difficult to complete everyday activities. Class 4 heart failure. Shortness of breath occurs even at rest. This category includes the most severe heart failure. It may be called end-stage or advanced congestive heart failure. American College of Cardiology/American Heart Association classification This stage-based classification system uses letters A to D. It includes a category for people who are at risk of developing heart failure. Stage A. There are several risk factors for heart failure but no signs or symptoms. Stage B. There is heart disease but no signs or symptoms of heart failure. Stage C. There is heart disease and signs or symptoms of heart failure. Stage D. There is heart disease and the symptoms disrupt daily life or lead to hospitalization. This stage is usually called end-stage or advanced congestive heart failure. Advanced heart failure requires specialized treatments. Healthcare professionals often use the staging systems together to help decide the right treatment for you. Your health professional can help you interpret your stage. Request an appointment Diagnosis & treatmentDoctors & departments Sept. 25, 2026 Share on: FacebookTwitter Living with heart failure? Connect with others like you for support and answers to your questions in the Heart & Blood Health support group on Mayo Clinic Connect, a patient community. Heart & Blood Health Discussions Stopping Carvedilol (Coreg): When will the effects wear off? 419 Replies Sat, Sep 26, 2026 chevron-right High Coronary Calcium Score: How do others feel emotionally? 697 Replies Thu, Sep 17, 2026 chevron-right Living with high calcium score 118 Replies Sat, Sep 12, 2026 chevron-right See more discussions Show references Ali A, et al. Prognostic value of quality of life and functional status in patients with heart failure: A systematic review and meta-analysis. The Egyptian Heart Journal. 2024; doi:10.1186/s43044-024-00532-z. Armstrong PW, et al. Vericiguat in patients with heart failure and reduced ejection fraction. New England Journal of Medicine. 2020; doi:10.1056/NEJMoa1915928. Baral R, et al. Exercise training improves exercise capacity and quality of life in heart failure with preserved ejection fraction: A systematic review and meta-analysis of randomized controlled trials. European Heart Journal Open. 2024; doi:10.1093/ehjopen/oeae033. Bodea OM, et al. Effects of SGLT2 inhibitors on clinical outcomes, symptoms, functional capacity, and cardiac remodeling in heart failure: A comprehensive systematic review and multidomain meta-analysis of randomized trials. Journal of Clinical Medicine. 2026; doi:10.3390/jcm15010378. Bohula EA, et al. Palliative and end-of-life care during critical cardiovascular illness: A scientific statement from the American Heart Association. Circulation. 2025; doi:10.1161/CIR.0000000000001334. Brown TM, et al. Core components of cardiac rehabilitation programs: 2024 update: A scientific statement from the American Heart Association and the American Association of Cardiovascular and Pulmonary Rehabilitation. Circulation. 2024; doi:10.1161/CIR.0000000000001289. Chuzi S, et al. Integration of palliative care into heart failure care: Consensus-based recommendations from the Heart Failure Society of America. Journal of Cardiac Failure. 2025; doi:10.1016/j.cardfail.2024.10.435. Symptom relief for the dying patient. Merck Manual Professional Version. https://www.merckmanuals.com/professional/special-subjects/the-dying-patient/symptom-relief-for-the-dying-patient. Accessed Aug. 26, 2026. The dying patient. Merck Manual Professional Version. https://www.merckmanuals.com/professional/special-subjects/the-dying-patient/the-dying-patient. Accessed Aug. 26, 2026. Coiro S, et al. Short- and long-term mortality in patients hospitalized for dyspnoea with acute heart failure, respiratory infection, or both: Insights from the PARADISE cohort. European Journal of Heart Failure. 2026; doi:10.1093/ejhf/xuag160. De Oliveira MT Jr, et al. Heart failure management with β-blockers: Can we do better? Current Medical Research and Opinion. 2024; doi:10.1080/03007995.2024.2318002. Drazner MH, et al. 2024 ACC expert consensus decision pathway on strategies and criteria for the diagnosis and management of myocarditis. Journal of the American College of Cardiology. 2025; doi:10.1016/j.jacc.2024.10.080. Fan X, et al. Stroke related brain–heart crosstalk: Pathophysiology, clinical implications, and underlying mechanisms. Advanced Science. 2024; doi:10.1002/advs.202307698. Acute heart failure. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/acute-heart-failure. Accessed Aug. 26, 2026. Chronic heart failure. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/chronic-heart-failure. Accessed Aug. 26, 2026. Heart transplantation. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/heart-transplantation. Accessed Aug. 26, 2026. Medications for heart failure. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/medications-for-heart-failure. Accessed Aug. 26, 2026. Overview of heart failure. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/overview-of-heart-failure. Accessed Aug. 26, 2026. Pulmonary edema. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/pulmonary-edema. Accessed Aug. 26, 2026. Right heart failure and cor pulmonale. Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/heart-failure/right-heart-failure-and-cor-pulmonale. Accessed Aug. 26, 2026. Fonarow GC, et al. HF STATS 2025: Heart failure epidemiology and outcomes statistics — An updated 2025 report from the Heart Failure Society of America. Journal of Cardiac Failure. 2026; doi:10.1016/j.cardfail.2025.07.007. Garred CH, et al. Age-specific mortality trends in heart failure over 25 years: A retrospective Danish nationwide cohort study. The Lancet Healthy Longevity. 2024; doi:10.1016/S2666-7568(24)00029-1. Giannakoulas G, et al. Acute right ventricular failure: Pathophysiology, aetiology, assessment, and management. European Heart Journal. 2025; doi:10.1093/eurheartj/ehaf215. Graven LJ, et al. Palliative care and advanced cardiovascular disease in adults: Not just end-of-life care: A scientific statement from the American Heart Association. Circulation. 2025; doi:10.1161/CIR.0000000000001323. Heidenreich PA, et al. 2022 AHA/ACC/HFSA guideline for the management of heart failure: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022; doi:10.1161/CIR.0000000000001063. Herrmann JJ, et al. Liberal fluid intake versus fluid restriction in chronic heart failure: A randomized clinical trial. Nature Medicine. 2025; doi:10.1038/s41591-025-03628-4. Hollenberg SM, et al. 2024 ACC expert consensus decision pathway on clinical assessment, management, and trajectory of patients hospitalized with heart failure focused update. Journal of the American College of Cardiology. 2024; doi:10.1016/j.jacc.2024.06.002. Irlik K, et al. Mortality and heart failure hospitalizations in heart failure with preserved ejection fraction compared to heart failure with reduced ejection fraction: A systematic review and meta-analysis. ESC Heart Failure. 2026; doi:10.1093/eschf/xvag026. Jones NR, et al. Survival of patients with chronic heart failure in the community: A systematic review and meta-analysis. European Journal of Heart Failure. 2019; doi:10.1002/ejhf.1594. Khan SS, et al. Risk-based primary prevention of heart failure: A scientific statement from the American Heart Association. Circulation. 2025; doi:10.1161/CIR.0000000000001307. Kittleson MM, et al. Management of heart failure with preserved ejection fraction: 2026 ACC expert consensus decision pathway. Journal of the American College of Cardiology. 2026; doi:10.1016/j.jacc.2026.06.018. Krishna BA, et al. Cardiovascular disease and COVID-19: A systematic review. International Journal of Cardiology Heart & Vasculature. 2024; doi:10.1016/j.ijcha.2024.101482. Maddox TM, et al. 2024 ACC expert consensus decision pathway for treatment of heart failure with reduced ejection fraction: A report of the American College of Cardiology Solution Set Oversight Committee. Journal of the American College of Cardiology. 2024; doi:10.1016/j.jacc.2023.12.024. Peled Y, et al. International Society for Heart and Lung Transplantation guidelines for the evaluation and care of cardiac transplant candidates — 2024. Journal of Heart and Lung Transplantation. 2024; doi:10.1016/j.healun.2024.05.010. Subramaniam A, et al. Advanced heart failure characteristics and outcomes in commercially insured U.S. adults. JACC: Heart Failure. 2023; doi:10.1016/j.jchf.2023.06.029. Tseng MCM, et al. Incidence and risk of cardiovascular outcomes in patients with anorexia nervosa. JAMA Network Open. 2024; doi:10.1001/jamanetworkopen.2024.51094. Walsh MN, et al. AHA/ACC/ESC/WHF expert consensus document: Second universal definition of heart failure (2026). Circulation. 2026; doi:10.1161/CIR.0000000000001455. Related Cardiac asthma: What causes it? Heart failure Heart failure and sex: Is it safe? Holiday Heart What is a heart failure action plan? Show more related content Associated Procedures Cardiac catheterization Cardiac resynchronization therapy Chest X-rays Coronary angiogram Coronary artery bypass graft CT scan Echocardiogram Electrocardiogram (ECG or EKG) Heart transplant Implantable cardioverter-defibrillators (ICDs) Intra-aortic balloon pump (IABP) MRI Pacemaker Palliative care Stress test Ventricular assist device Show more associated procedures News from Mayo Clinic Research study shows the cost-effectiveness of AI-enhanced heart failure screening Enhancing care for heart failure patients through a data-driven approach 'Virtual clinical trials' may predict success of heart failure drugs Mayo Clinic researchers identify a new stem cell patch to gently heal damaged hearts Show more news from Mayo Clinic Products & Services A Book: Future Care Heart failureSymptoms&causesDiagnosis&treatmentStagesDoctors&departmentsCare atMayoClinic CON-20373117 Diseases & Conditions Heart failure