Ameloblastoma diagnosis might begin with tests such as:

  • Imaging tests. X-ray, CT and MRI scans help doctors determine the extent of an ameloblastoma. The tumor can sometimes be found on routine X-rays at the dentist's office.
  • Tissue test. To confirm the diagnosis, doctors may remove a sample of tissue or a sample of cells and send it to a lab for testing.


Ameloblastoma treatment may depend on your tumor's size and location, and the type and appearance of the cells involved. Treatment may include:

  • Surgery to remove the tumor. Ameloblastoma treatment usually includes surgery to remove the tumor. Ameloblastoma often grows into the nearby jawbone, so surgeons may need to remove the affected part of the jawbone. An aggressive approach to surgery reduces the risk that ameloblastoma will come back.
  • Surgery to repair the jaw. If surgery involves removing part of your jawbone, surgeons can repair and reconstruct the jaw. This can help improve how your jaw looks and works afterward. The surgery can also help you to be able to eat and speak.
  • Radiation therapy. Radiation therapy using high-powered energy beams might be needed after surgery or if surgery isn't an option.
  • Prosthetics. Specialists called prosthodontists can make artificial replacements for missing teeth or other damaged natural structures in the mouth.
  • Supportive care. A variety of specialists can help you work through speaking, swallowing and eating problems during and after treatment. These specialists may include dietitians, speech and language therapists, and physical therapists.

Due to the risk of recurrence after treatment, lifelong, regular follow-up appointments are important.

Ameloblastoma care at Mayo Clinic

Nov. 17, 2021
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