Cutaneous T-cell lymphoma care at Mayo Clinic

Mayo Clinic Cutaneous Lymphoma Specialty Clinic

[MUSIC PLAYING]

Shannon Piche, Pharm.D., Clinical Pharmacist: What I hope that a patient feels is that things are different here. They come to Mayo Clinic and we honor the things that are important to the patient. We hear them, we understand, we see their journey.

N. Nora Bennani, M.D., Hematologist, Internist & Oncologist: Some of these cutaneous lymphomas are notoriously difficult to manage. There are a lot of symptoms that can be difficult to treat, particularly the itching. Having a dermatologist, a hematologist, pharmacist, as well as a radiation oncologist see the patient at the same time and come up with the plan relatively quickly is of tremendous help to the patient.

Nneka I. Comfere, M.D., Dermatologist: Oftentimes, patients are frustrated because they've spent a lot of time away from work and family and just the burden associated with trialing different treatments that haven't really worked because the diagnosis was never really clear.

Dr. Piche: When you come to Mayo, you still have a rare condition, but you're one of a few more, at least. The providers that are caring for you have years and years of caring for this specific type of illness and you're in a specialty clinic that literally is focused on you.

Dr. Bennani: When we see a patient here at Mayo Clinic, we look at the patient as a whole.

Emma F. Johnson, M.D., Dermatologist: This allows us to sit with the patient and hear their story, their journey and how this is impacting them and how we can help them feel better.

William G. Breen, M.D., Radiation Oncologist: I think it's comforting to patients to know that there's doctors from different specialties and different expertises, putting their heads together to try to come up with what's the best plan right now.

Dr. Comfere: Second to our multidisciplinary and patient-centered approach to care, I would say another differentiator for our Cutaneous Lymphoma Clinic is access to clinical trials.

Dr. Bennani: A clinical trial may provide you with highly active therapies that will not be available to you outside of a trial. I will highly encourage our patients to consider looking into it.

Dr. Breen: We're fortunate enough in our department of radiation oncology to have access to a number of different treatment modalities that aren't available at most centers in the region or the country.

Dr. Comfere: We're really excited about this new piece of skin imaging technology we've brought into our practice. It takes a picture of the entirety of the skin soft surface in one shot, so right away it gives you a sense of the proportion of the surface of the skin that's involved by lymphoma.

Dr. Johnson: Each patient with cutaneous lymphoma is going to require different treatment. It can range from topical creams and light therapy to chemotherapy and radiation, so really wide spectrum of treatments. And by considering the patient as a whole and from multiple different perspectives, we can select the appropriate treatment on that broad spectrum.

Dr. Breen: When we're treating a patient with cutaneous lymphoma, of course the focus is treating the lymphoma and making sure that we're safely and effectively treating the lymphoma, but patients are also real people who have other things going on in life.

Dr. Piche: Hearing from the patient what their priorities are and what their barriers are to implementing a particular recommendation is very important. So you have to work with a patient to create a regimen that is tolerable for them and their lifestyle.

Dr. Johnson: Because it can be so symptomatic, we really let the patient guide treatment with which symptoms they want to treat first or most aggressively. When a patient finishes their visit at Mayo Clinic, we hope that we have a solid diagnosis. The patient understands that diagnosis and what that means for them now and also in the future.

Dr. Bennani: And ultimately we wanna do what's best for our patients, whether they are treated here at Mayo or we are helping their local team in the community manage their disease.

Dr. Breen: We know that there's so much variation from cancer type to cancer type and patient to patient that it's really important to hear from an expert about what's the reality of your diagnosis.

Dr. Comfere: They're in the right place, and I tell them, we've seen many, many cases of this cutaneous lymphoma and we know how to diagnose it, and we know how to treat it, and we're going to help their local providers and equip them with the resources they need to follow their care over time.

Dr. Johnson: I think treatment success is guided by the patient, so if we are able to get them back to living a life that they enjoy, that they can do the things that they want to do, that is my goal.

Mayo Clinic lymphoma doctors have the experience to provide you with expert care that meets all your needs. Mayo Clinic Comprehensive Cancer Center offers a full range of treatments so that you and your care team can choose the treatment plan that's right for you.

Your Mayo Clinic care team

At Mayo Clinic, doctors who are specialists in dermatology, hematology, pathology, radiology, oncology and radiation oncology work with other experts to create a plan for your care. Members of your care team also consider what you want and your goals as they decide what treatment is right for you.

Advanced diagnosis and treatment

Mayo Clinic doctors and other healthcare professionals use the latest in laboratory techniques to provide you with an accurate diagnosis. Advanced tests may be used to analyze your cancer cells to guide treatment and give clues about your prognosis.

Your care team considers all the available options when personalizing a treatment plan. You have access to a full range of treatments, including light therapy, radiation therapy, bone marrow transplant and medicines, such as chemotherapy, immunotherapy and targeted therapy.

Expertise and rankings

Mayo Clinic doctors have experience diagnosing and treating rare cancers, including cutaneous T-cell lymphoma. When you seek care here, you can expect:

  • Personalized care. At Mayo Clinic, dermatologists, hematologists, radiation oncologists, pathologists and radiologists work as a multidisciplinary team to create a care plan that takes all your needs into consideration. Other doctors and healthcare professionals are included as needed.
  • Experience you can trust. Because cutaneous T-cell lymphoma is rare, few doctors have diagnosed it or treated a person with cutaneous T-cell lymphoma. But Mayo Clinic experts have diagnosed and treated many people with this disease.

Nationally recognized expertise

Mayo Clinic Comprehensive Cancer Center meets the strict standards for a U.S. National Cancer Institute comprehensive cancer center. These standards recognize scientific excellence and a multispecialty approach focused on cancer prevention, diagnosis and treatment.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, are ranked among the Best Hospitals for cancer by U.S. News & World Report. Mayo Clinic in Rochester, Minnesota, is ranked as the top hospital in Minnesota and Mayo Clinic in Phoenix/Scottsdale, Arizona, is ranked as the top hospital in Arizona.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

April 29, 2026

Living with cutaneous T-cell lymphoma?

Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community.

Blood Cancers & Disorders Discussions

hikerny
Anyone have chronic lymphocytic leukemia (CLL)?

253 Replies Sat, May 02, 2026

Lori, Volunteer Mentor
My Bone Marrow Transplant (BMT/SCT) story: Will you share yours?

862 Replies Sat, May 02, 2026

fortuitous
Does anyone else have AML with ddx41 genetic mutation?

21 Replies Fri, May 01, 2026

See more discussions

Related

Associated Procedures

Products & Services