Physical Medicine and Rehabilitation

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study of the Safety of Joint Injected Sc-rAAV2.5IL-1Ra (a Virus Carried Gene Therapy) in Patients with Moderate Knee Osteoarthritis

   Rochester, Minn.

   The purpose of this study is to determine the safety of sc-rAAV2.5IL-1Ra, a gene therapy carried by a virus and delivered by injection into the knee joint of patients with moderate osteoarthritis of the knee.

2. A Study to Evaluate Physical Therapy in the Emergency Department

   Rochester, Minn.

   The purpose of this study is to determine the utility of physical therapy services in the Emergency Department through a prospective satisfaction survey of both providers and patients with physical therapy provided in the emergency department.

3. Spinal Cord Injury and Dysfunction Registry: Acute Injury Through Life Long Care

   Rochester, Minn.

   The purpose of this project is to create and implement a Mayo Clinic spinal cord injury registry that allows team members to collect, sort and analyze patient and program information from acute spinal cord injury through lifelong follow-up.  The data will be used both clinically (for program assessment and federally required reporting) and individual research projects (e.g., patient outcomes).

4. Evaluation of a Tele-Language Rehabilitation Program

   Rochester, Minn.

   The aims of this study are to assess the feasibility of and satisfaction with providing a tele-rehabilitation service directed at language disorders in individuals with stroke and measure the change in language function.

5. Study to Determine Whether Cancer Symptom Control can be Enhanced Using Electronic Health Records

   Rochester, Minn.

   The purpose of this study is to determine whether control of moderate or worse sleep disturbance, pain, anxiety, depression, and fatigue among cancer survivors and patients with cancer will improve quality of life, symptom severity, function, and adherence to cancer treatment, and reduced health care utilization.

6. A Study of Traditional Korean Medicine Effectiveness in Comparison to Non-Surgical Conventional Standard Treatment for Patients with Lumbar Spinal Spondylolisthesis

   Rochester, Minn.

   This research is being done, in a joint-effort between Mayo Clinic and the Mokhuri Oriental Medical Hospital, to evaluate the effectiveness and safety of two different types of non-surgical treatment in patients with symptomatic lumbar spinal spondylolisthesis.

7. A Study to Evaluate The Role of Physical and Occupational Therapy Home Evaluations and Fall Incidence Post Discharge from Inpatient Rehabilitation Facility

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to examine the effectiveness of home evaluations following inpatient rehabilitation facility (IRF) discharge in reducing falls as compared to patients who were discharged home that did not complete a home evaluation.

8. A Study to Evaluate the Effects of Physical Therapy on Patients Treated with Surgery (Periacetabular Osteotomy or PAO) for Developmental Dysplasia of the Hip (DDH)

   Rochester, Minn.

   The purpose of this study is to assess perioperative and postoperative outcomes to date in patients treated with surgery (Periacetabular Osteotomy or PAO) for Developmental Dysplasia of the Hip (DDH) receiving formal postoperative physical therapy versus those patients who did not receive formal postoperative physical therapy.

9. A Study to Evaluate Meniscal Extrusion with and without Medial Knee Unloader Bracing Using Ultrasound

   Minneapolis, Minn.

   The purpose of this study is to quantify medial meniscal extrusion with and without a medial knee unloader brace using ultrasonography in patients with isolated medial knee pain.

10. Medical and Resource Facilitation Intervention After Traumatic Brain Injury

    Rochester, Minn.

    Mayo Clinic's Traumatic Brain Injury (TBI) Model System Center (TBIMSC) will capitalize on longstanding collaborations with the non-profit Minnesota Brain Injury Alliance (MN BIA) and Minnesota Department of Health (MDH) to test a new way of delivering medical and social services. This trial will address chronic unmet needs expressed by individuals with TBI and their families in the U.S. pertaining to the ineffective connection to specialized medical and community resources in the transition from hospital to community-based care, limited access to TBI experts, and lack of primary care provider (PCP) knowledge about the complex needs of individuals with TBI. Target populations for this study are: 1) individuals with TBI eligible for MN BIA provided Resource Facilitation (RF), 2) their families, and 3) their PCPs. This clinical trial will use a theory-driven complex behavioral intervention that integrates the medical-rehabilitation, therapy, and TBI expertise of Mayo's Brain Rehabilitation Clinic (BRC) with MN BIA's highly developed RF program (a free two-year telephone support service offering assistance in navigating life after brain injury). Mayo Clinic's medical-rehabilitation expertise will be integrated with RF services to deliver direct clinical care remotely using telemedicine and other information and communication technology to test whether outcomes over time are better in a group receiving this model of care compared to a group that receives usual care in their communities. Costs between usual care and intervention groups will be compared in collaboration with the MDH. The overarching goal is development of a replicable, sustainable, and cost effective model of telemedicine care that integrates TBIMS Centers and BIAs nationwide and builds TBI expertise and capacity among PCPs.