Physical Medicine and Rehabilitation

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. A Study to Evaluate Physical Therapy in the Emergency Department

   Rochester, Minn.

   The purpose of this study is to determine the utility of physical therapy services in the Emergency Department through a prospective satisfaction survey of both providers and patients with physical therapy provided in the emergency department.

2. A Study of the Safety of Joint Injected Sc-rAAV2.5IL-1Ra (a Virus Carried Gene Therapy) in Patients with Moderate Knee Osteoarthritis

   Rochester, Minn.

   The purpose of this study is to determine the safety of sc-rAAV2.5IL-1Ra, a gene therapy carried by a virus and delivered by injection into the knee joint of patients with moderate osteoarthritis of the knee.

3. Spinal Cord Injury and Dysfunction Registry: Acute Injury Through Life Long Care

   Rochester, Minn.

   The purpose of this project is to create and implement a Mayo Clinic spinal cord injury registry that allows team members to collect, sort and analyze patient and program information from acute spinal cord injury through lifelong follow-up.  The data will be used both clinically (for program assessment and federally required reporting) and individual research projects (e.g., patient outcomes).

4. Evaluation of a Tele-Language Rehabilitation Program

   Rochester, Minn.

   The aims of this study are to assess the feasibility of and satisfaction with providing a tele-rehabilitation service directed at language disorders in individuals with stroke and measure the change in language function.

5. A Study to Evaluate the Effects of Physical Therapy on Patients Treated with Surgery (Periacetabular Osteotomy or PAO) for Developmental Dysplasia of the Hip (DDH)

   Rochester, Minn.

   The purpose of this study is to assess perioperative and postoperative outcomes to date in patients treated with surgery (Periacetabular Osteotomy or PAO) for Developmental Dysplasia of the Hip (DDH) receiving formal postoperative physical therapy versus those patients who did not receive formal postoperative physical therapy.

6. A Study to Evaluate The Role of Physical and Occupational Therapy Home Evaluations and Fall Incidence Post Discharge from Inpatient Rehabilitation Facility

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to examine the effectiveness of home evaluations following inpatient rehabilitation facility (IRF) discharge in reducing falls as compared to patients who were discharged home that did not complete a home evaluation.

7. Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial 

   Rochester, Minn.

   The Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial will determine whether systematically assessing patient reported outcomes for sleep disturbance, pain, anxiety, depression, and fatigue among patients with solid and liquid malignancies and using these data to increase the frequency of guideline-concordant care by: 1) reporting these data to their clinical teams, 2) providing patients with needs-matched symptom self-management education, and 3) suggesting evidence-based symptom management strategies to their care teams improves patients' quality of life, symptoms, and adherence to cancer treatment, while reducing their unplanned use of healthcare resources.

    

8. A Study to Evaluate Meniscal Extrusion with and without Medial Knee Unloader Bracing Using Ultrasound

   Minneapolis, Minn.

   The purpose of this study is to quantify medial meniscal extrusion with and without a medial knee unloader brace using ultrasonography in patients with isolated medial knee pain.

9. A Study to Evaluate the Effectiveness of Diaphragmatic Breathing on Reflux Symptoms in Outpatients

   Jacksonville, Fla.

   The purpose of this study is to establish if abdominal breathing exercises can reduce symptoms associated with reflux.

10. Medical and Resource Facilitation Intervention After Traumatic Brain Injury

    Rochester, Minn.

    Mayo Clinic's Traumatic Brain Injury (TBI) Model System Center (TBIMSC) will capitalize on longstanding collaborations with the non-profit Minnesota Brain Injury Alliance (MN BIA) and Minnesota Department of Health (MDH) to test a new way of delivering medical and social services. This trial will address chronic unmet needs expressed by individuals with TBI and their families in the U.S. pertaining to the ineffective connection to specialized medical and community resources in the transition from hospital to community-based care, limited access to TBI experts, and lack of primary care provider (PCP) knowledge about the complex needs of individuals with TBI. Target populations for this study are: 1) individuals with TBI eligible for MN BIA provided Resource Facilitation (RF), 2) their families, and 3) their PCPs. This clinical trial will use a theory-driven complex behavioral intervention that integrates the medical-rehabilitation, therapy, and TBI expertise of Mayo's Brain Rehabilitation Clinic (BRC) with MN BIA's highly developed RF program (a free two-year telephone support service offering assistance in navigating life after brain injury). Mayo Clinic's medical-rehabilitation expertise will be integrated with RF services to deliver direct clinical care remotely using telemedicine and other information and communication technology to test whether outcomes over time are better in a group receiving this model of care compared to a group that receives usual care in their communities. Costs between usual care and intervention groups will be compared in collaboration with the MDH. The overarching goal is development of a replicable, sustainable, and cost effective model of telemedicine care that integrates TBIMS Centers and BIAs nationwide and builds TBI expertise and capacity among PCPs.