Multiple Sclerosis and Autoimmune Neurology Overview

People with multiple sclerosis or related conditions benefit from the advanced diagnostic and treatment expertise of the neurologists in the Division of Multiple Sclerosis and Autoimmune Neurology. Our multiple sclerosis care teams help thousands of adults and children each year. Mayo Clinic in Rochester, Minnesota, has a specialized Pediatric Multiple Sclerosis Center.

Multiple sclerosis, also called MS, is a disease in which the immune system attacks the covering surrounding the nerves in your brain and spinal cord. This covering is called the myelin sheath. These nerves send information from your brain and spinal cord to other nerves in your body, and myelin helps make this transmission efficient. Multiple sclerosis and several other conditions cause damage to the myelin. Thus they are called demyelinating diseases.

Your care team

Your neurologist brings together a multispecialty team that might include experts in physical medicine and rehabilitation, urologists, psychiatrists, neuro-ophthalmologists, and others. This team listens to you and works to ensure you get exactly the care you need.

People with multiple sclerosis and related conditions benefit from this team-based approach, tailored to their needs, as symptoms can affect multiple body systems and cause weakness, walking problems, muscle stiffness and bladder problems. Our caring team can help you with your multiple sclerosis-related health concerns.

Conditions

Research advances that improve clinical care

Our physician-scientists and other researchers have long been leaders in advancing the understanding and treatment of MS and other demyelinating diseases. They conduct clinical research, laboratory studies and clinical trials to study causes, genetics, disease progression and potential new treatments.

Staff in the Center for Multiple Sclerosis and Autoimmune Neurology conducts research in MS and other related conditions.

Researchers also study evaluation and treatment options for children with multiple sclerosis at Mayo Clinic in Rochester, Minnesota.

Nationally recognized expertise

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, rank among the Best Hospitals for neurology and neurosurgery in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic Children's in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2024-2025 "Best Children's Hospitals" rankings.

Mayo Clinic is ranked more than any other hospital and has been recognized as an Honor Roll member according to the U.S. News & World Report's "Best Hospitals" rankings.

Why choose Mayo Clinic for multiple sclerosis care

[MUSIC PLAYING]

[Sean J. Pittock, M.D., Chair, Department of Neurology]

Mayo Clinic has a very long tradition of providing excellent care for patients with multiple sclerosis. In fact, we were very much involved in some of the very early research that was done in the disease, but we've also been leading the field, in terms of practice, in terms of providing care for patients.

[Eoin P. Flanagan, M.B., B.Ch., Neurologist]

We see about 3,500 patients a year, and we have great expertise in ensuring that we have the correct diagnosis and we know which treatment is best for which patient. So I think coming here and getting that treatment correct at the start is very important.

[Dr. Pittock] Patients that come to the Mayo Clinic become part of the answer in terms of the research that's going on at the Mayo Clinic, because the Mayo Clinic has the largest biorepository of MS and autoimmune neurological disorders in the world.

[Dr. Flanagan] There are many patients out there who come to Mayo Clinic and Mayo Clinic is their last hope.

We can really control MS much better than we used to be able to.

[Dr. Pittock] Well I think the future is bright.

We've made dramatic advances.

We now have drugs that reduce the chances of a clinical relapse by 98.5%.

That's pretty amazing.

[Dr. Flanagan] We know that multiple sclerosis can affect a lot of parts of the nervous system ranging from vision, to walking to bladder, stiffness, cognition.

We can measure nerve damage.

We can treat things like muscle stiffness or spasticity.

Mayo Clinic can offer a lot for patients in new diagnosis, but also in patients with an established diagnosis, maybe with some damage that we can ensure that we can manage all of those symptoms excellently. And that's where our multidisciplinary care really is a distinguisher for us.

[Dr. Pittock] You don't just see a neurologist, you see a multitude of different individuals, all of whom have specialty experience within the care of multiple sclerosis patients.

[Dr. Flanagan] It's the neurologist talking to the physical medicine rehab team, talking to the ophthalmologist, talking to the urologist to come up with the best plan for the patient.

[Dr. Pittock] We're working with physiatrists.

We're working with people that work in bio-electronics to try and develop approaches that we can use to not only stopping the progression of the disease, but restoring function.

[MUSIC STOPS]

Contact

Arizona

  • Multiple Sclerosis Clinic for Adults
  • Mayo Clinic
  • 13400 E. Shea Blvd.
    Scottsdale, AZ 85259
  • Phone: 480-301-8000

Florida

  • Multiple Sclerosis and Autoimmune Neurology
  • Mayo Clinic
  • 4500 San Pablo Road
    Jacksonville, FL 32224
  • Phone: 904-953-0856

Minnesota

  • Multiple Sclerosis and Autoimmune Neurology
  • Mayo Clinic
  • 200 First St. SW
    Eighth Floor
    Rochester, MN 55905
  • Phone: 507-284-2111
March 22, 2025