Clinical trials Below are current clinical trials.89 studies in Breast Clinic (open studies only). Filter this list of studies by location, status and more. A Study to Evaluate Chemotherapy-Induced Nausea in Breast Cancer Patients Scottsdale/Phoenix, Ariz. The purpose of the study is to alleviate the occurrence of chemotherapy-induced nausea (CIN) and to improve chemotherapy treatment outcomes. Recent research has shown that changes in the functions performed by the gut microbiome can cause the occurrence of chemotherapy-induced symptoms that include chemotherapy-induced nausea. A Study of Vulvovaginal Symptoms in Premenopausal Stage 0-III Breast Cancer Patients Treated on Aromatase Inhibitors and Ovarian Suppression Jacksonville, Fla. The purpose of this study is to evaluate the change of vulvovaginal symptoms score from baseline to 6 months in premenopausal women with stage 0-III breast cancer treating with ovarian suppression in combination with aromatase inhibitors. A Study to Evaluate Factors in Breast Cancer Screening Among Asian Americans in Olmsted and Surrounding Counties Rochester, Minn. The purpose of this study is to assess the effect of acculturation, socio-economic status (SES) and place of residence (urban vs. rural) on the level of participation in breast cancer screening programs and on the breast cancer knowledge and beliefs among Asian American women in Olmsted and surrounding counties. A Study of TAS-120 in Patients With Metastatic Breast Cancer Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to assess the antitumor activity of TAS-120 as monotherapy or in combination with Fulvestrant in the treatment of patients with metastatic breast cancer harboring fibroblast growth factor receptor (FGFR) amplifications. A Study Assessing the Effectiveness and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced Triple Negative Breast Cancer Rochester, Minn., Scottsdale/Phoenix, Ariz. The purpose of this study is to determine whether treatment with alpelisib in combination with nab-paclitaxel is safe and effective in subjects with advanced triple negative breast cancer (aTNBC) who carry either a PIK3CA mutation (Study Part A) or have PTEN loss without PIK3CA mutation (Study Parts B1 and B2) A Study to Evaluate ctDNA Diagnostics in Recurrent Breast Cancer Patients Rochester, Minn. The purpose of this study is to to establish a minimally-invasive blood based test for the detection of clinically actionable genetic changes in breast cancer patients. Understanding the Relationship Between Benign Breast Tissue, Benign Breast Disease, and Breast Cancer Development Jacksonville, Fla. The purpose of this study is to culture human mammary cells to identify cellular characteristics associated with lobular involution status. Estradiol in Treating Patients With ER Beta Positive, Triple Negative Locally Advanced or Metastatic Breast Cancer Jacksonville, Fla., Rochester, Minn. The purpose of this trial is to determine how well estradiol works in treating patients with estrogen receptor beta (ER beta) positive, triple negative breast cancer that has spread to nearby tissue or lymph nodes (locally advanced) or other places in the body (metastatic). Hormone receptors like ER beta allow the body to respond appropriately to hormones. Triple negative means that the breast cancer does not express other hormone receptors called ER alpha, progesterone, and HER2. In some people with triple negative breast cancer, ER beta is overexpressed. Tumor cells that overexpress ER beta grow slower in the laboratory and this growth is slowed in the presence of estrogen. Estradiol is a form of estrogen. This study may help doctors determine whether tumor cells that overexpress ER beta shrink in the presence of estradiol. A Study to Evaluate User Feedback Using Affirm® Contrast Biopsy Scottsdale/Phoenix, Ariz. The purpose of this study is to collect user and subject feedback on the design, use and operation of Affirm® Contrast Biopsy. Comparison of Operation to Monitoring With/Without Endocrine Therapy For Low Risk DCIS Jacksonville, Fla., Rochester, Minn., Scottsdale/Phoenix, Ariz. This study looks at the risks and benefits of active surveillance (AS) compared to guideline concordant care (GCC) in the setting of a pragmatic prospective randomized trial for low risk DCIS. Our overarching hypothesis is that management of low-risk Ductal Carcinoma in Situ (DCIS) using an AS approach does not yield inferior cancer or quality of life outcomes compared to GCC. Pagination Clinical studies Go to page 11 Go to page 22 Go to page 33 Go to page 44 Go to page 55 NextNext Page Request an Appointment at Mayo Clinic Locations, travel & lodgingResearch April 22, 2022 Share on: FacebookTwitter Show references National Accreditation Program for Breast Centers. American College of Surgeons. https://www.facs.org/quality-programs/napbc. Accessed Feb. 7, 2019. Breast SPOREs. National Cancer Institute. https://trp.cancer.gov/spores/breast.htm. Accessed Feb. 7, 2019. Find an NCI-designated cancer center. National Cancer Institute. https://www.cancer.gov/research/nci-role/cancer-centers/find. Accessed Feb. 7, 2019. 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