Biographical summary
Mark J. Truty, M.D., M.S., is a cancer surgeon recognized for his commitment to offering hope where others have seen limits. His practice centers on complex abdominal tumors, and he is known for combining advanced surgical techniques with thoughtful preoperative strategies to improve patient outcomes. Patients and referring physicians seek him out for his ability to perform curative-intent operations, even in cases previously deemed inoperable due to involvement of critical blood vessels.
Areas of Expertise
Dr. Truty provides comprehensive surgical care for patients with challenging and advanced tumors. His clinical focus includes:
- Pancreatic cancer: Specialized in complex resections and preoperative treatment plans to optimize surgical success.
- Liver tumors: Expertise in managing primary and metastatic liver cancers with advanced surgical approaches.
- Biliary tumors: Skilled in treating cancers affecting bile ducts with precision and multidisciplinary care.
- Gastric cancer: Offers tailored surgical solutions for stomach tumors, focusing on long-term outcomes.
- Small bowel and carcinoid tumors: Experienced in managing rare and complex intestinal cancers.
- Sarcoma tumors: Provides surgical care for soft tissue sarcomas involving critical vascular structures.
Research and Commitment to Better Outcomes
Dr. Truty’s work reflects a deep commitment to advancing surgical care for patients with complex cancers. His research focuses on improving preoperative treatment strategies and refining surgical techniques to achieve better survival and quality of life. By redefining what’s possible in complex cancer care, he helps patients access treatments once thought out of reach.
Conditions treated
Procedures performed
Interests
- Multidisciplinary surgical management of complex and/or advanced pancreatic, liver, bile duct, gallbladder, carcinoid, gastric and intestinal tumors and sarcomas
- Benign and malignant disease of liver, biliary tree, gallbladder and pancreas
- Neuroendocrine tumors
Mayo Clinic locations
Education
- 2022
Certificate - Tableau Data VisualizationsCenter for Advanced Computing, Cornell University
- 2021
Certificate - The Business of Healthcare Specialization CertificateWharton School of Business, University of Pennsylvania
- 2012
Chief FellowUniversity of Texas M.D. Anderson Cancer Center
- 2012
Postdoctoral Research Fellowship - Patient-Based Biological Research ProgramUniversity of Texas M.D. Anderson Cancer Center
- 2012
Fellow - Advanced Surgical OncologyUniversity of Texas M.D. Anderson Cancer Center
- 2009
Chief Resident - General SurgerySurgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2009
Internship and Junior ResidencySurgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2009
ResidentSurgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2009
Senior ResidentSurgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2006
Clinical InvestigatorClinician Investigator, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2006
Postdoctoral Research FellowshipGastroenterology Research Unit, Division of Gastroenterology and Hepatology, Department of Internal Medicine
- 2006
ResidentClinician Investigator, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2004
ResidentSurgery, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2002
Master of Science - PathologyChicago Medical School
- 2002
Doctorate of Medicine - MedicineChicago Medical School
- 1998
Master of Science - PhysiologyChicago Medical School
- 1996
Bachelor - Biological SciencesUniversity of Chicago
Activities and honors
Certifications
- 2010
General SurgeryAmerican Board of Surgery
Awards and honors
- 2023
2023 PanCAN Research AwardPancreas Club
- 2023
2023 PanCAN Research AwardPancreas Club
- 2022
Best Poster of IHPBAIHPBA
- 2021
Best of AJR Award American Journal of Radiology
- 2019
J. Bradley Aust AwardWestern Surgical Association
- 2018
Most Outstanding Faculty Teacher of the YearGeneral Surgery, Department of Surgery
- 2014
Teacher of the Year - Surgical SubspecialtiesMayo Fellows Association, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
- 2013
Most Outstanding Faculty Teacher of the YearGeneral Surgery, Department of Surgery
- 2013
Most Outstanding Faculty Teacher of the YearMayo School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Department of Education Administration
- 2013
Best in Category (Liver)International Anesthesia Research Society
- 2012
Poster of DistinctionPancreas Club
- 2012
Poster of DistinctionPancreas Club
- 2011
Best Oral Presentation of Clinical or Basic Science in Pancreatic CancerPancreas Cancer Action Network, Pancreas Club
- 2010
Mayo Foundation ScholarMayo Clinic College of Medicine and Science, Department of Education Administration
- 2010
Paul Calabresi Clinician Investigator ScholarMayo Clinic College of Medicine and Science, Department of Education Administration
- 2009
Most Outstanding Chief Resident Teacher of the YearGeneral Surgery, Department of Surgery
- 2009
Donald C. Balfour Most Outstanding Research AwardMayo Clinic Alumni Association, Mayo Clinic College of Medicine and Science, Department of Education Administration
- 2008
Leadership Award ScholarshipResident and Associate Society, American College of Surgeons
- 2008
Most Outstanding Clinical and Technical Surgical ResidentHoward K. Gray Travel Award
- 2007
Travel Scholarship AwardNational Pancreas Foundation
- 2007
Best Oral Presentation by a New Member of the AAS.Academic Surgical Congress
- 2007
American College of Surgeons - Surgical Jeopardy FinalistAcademic Surgical Congress
- 2006
Hungry Dog Award - Department of SurgeryGeneral Surgery Residency Program, Programs in Rochester, Mayo School of Graduate Medical Education
- 2006
Best Resident Research Presentation Inlow AwardPriestley Society, Mayo Clinic Rochester Societies
- 2006
Most Outstanding Basic Science Research AwardMinnesota Surgical Society
- 2006
Most Outstanding Surgical Research AwardBalfour Research Symposium
- 2006
Travel Scholarship AwardAmerican Pancreatic Association/International Association of Pancreatology
- 2005
Outstanding Young Investigator Research AwardHartz Foundation
- 2004
Outstanding Medical Student EducatorMayo Clinic College of Medicine and Science, Department of Education Administration
- 2003
Most Outstanding Junior Resident - Silver Retractor AwardMayo Clinic College of Medicine and Science, Department of Education Administration
- 2003
Most Outstanding Clinical Research AwardMinnesota Surgical Society
- 2003
Resident Travel ScholarshipAmerican College of Surgeons
- 2002
Alpha Omega AlphaChicago Medical School
- 2002
Board of Trustees Academic Scholarship AwardChicago Medical School
- 2002
Mayo Clinic Frankel Academic ScholarshipMayo Clinic College of Medicine and Science, Department of Education Administration
- 1999
Top 10% Academic PerformanceChicago Medical School
Professional memberships
- 2025 - 2026
Audit ChairWestern Surgical Association
- 2023 - present
2nd Vice PresidentWestern Surgical Association
- 2023 - present
Medical EditorDivision of Health Education and Content Services
- 2022 - present
Committee MemberMayo Clinic Rochester, Clinical Practice Committee, OmniView Clinical Selection Committee
- 2022 - present
HPB DG Executive CommitteeMayo Clinic Cancer Center
- 2022 - present
HPB DG Executive CommitteeMayo Clinic Cancer Center
- 2022 - present
Pancreatic Adenocarcinoma Guidelines Committee MemberNational Cancer Center Network
- 2021 - present
ChairHPB Tumor Board
- 2021 - present
MemberNational Comprehensive Cancer Network (NCCN) Pancreatic Adenocarcinoma Panel
- 2021 - present
ChairPancreas eTumor Board
- 2021 - present
Medical DirectorClinical Practice Committee
- 2019 - present
Co-ChairPancreas/Neuroendocrine 3-site Disease/Discipline Oriented Groups (DOGs)
- 2018 - present
Program Committee MemberAmericas Hepatobiliary Association (AHPBA)
- 2018 - present
Program CommitteeAmericas Hepatobiliary Association (AHPBA)
- 2017 - present
MemberConnective Tissue Oncology Society
- 2017 - present
Executive Committee MemberEsophageal/Gastric 3-site Disease/Discipline Oriented Groups (DOGs)
- 2017 - 2019
Executive Committee MemberPancreas/Neuroendocrine 3-Site Disease/Discipline Oriented Groups (DOGs)
- 2017 - 2019
Co-ChairSarcoma Disease/Discipline Oriented Groups (DOGs)
- 2016 - present
MemberAmerican Gastroenterological Association (AGA)
- 2015 - 2017
Program CommitteePancreas Club
- 2015 - 2017
ChairMayo Clinic Center for Individualized Medicine Pancreatic Cancer Discovery Team
- 2015 - present
MemberPriestley Society
- 2014 - 2016
Program Committee RepresentativePancreas Club
- 2014 - present
MemberMayo Clinic Cancer Center
- 2014 - present
MemberAmerican College of Surgeons
- 2013 - 2020
Medical Director - Francis 1C/2CClinical Practice Committee, Saint Marys Hospital
- 2013 - present
Surgical RepresentativeEquipment Subcommittee, Clinical Practice Committee - Rochester
- 2013 - present
Committee MemberHome Enteral Nutrition Steering Committee
- 2012 - present
Surgical RepresentativeMayo Clinic SPORE in Pancreatic Cancer, Mayo Clinic Cancer Center
- 2010
CandidateAmerican Radium Society
- 2010 - present
MemberUniversity of Chicago Alumni Association, University of Chicago
- 2009 - present
MemberSociety of Surgical Oncology
- 2009 - present
MemberAmerican Society of Clinical Oncology
- 2006 - 2007
Past PresidentMayo Fellows Association, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine and Science
- 2006 - present
MemberAmerican Association for Cancer Research
- 2006 - present
MemberAmerican Hepato-Pancreato-Biliary Association
- 2006 - present
MemberSociety of American Gastrointestinal and Endoscopic Surgeons
- 2005 - 2010
MemberAmerican Pancreatic Association
- 2005 - 2009
MemberAssociation for Academic Surgery
- 2005 - present
MemberSociety for Surgery of the Alimentary Tract
- 2005 - present
MemberPancreas Club
- 2004 - 2006
PresidentMayo Fellows Association, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine and Science
- 2004 - 2006
Resident RepresentativeMinnesota Medical Association
- 2004 - 2006
Resident RepresentativeAmerican Medical Association
- 2004 - 2005
Resident RepresentativeZumbro Valley Medical Society, Minnesota Medical Association
- 2002 - present
MemberAmerican Medical Association
- 2002 - present
MemberZumbro Valley Medical Society, Minnesota Medical Association
- 2002 - present
MemberMinnesota Medical Association
Publications
Research activities