Terence T. Sio, M.D., M.S.

  1. Oncologist
  2. Radiation Oncologist

Departments

  1. Radiation Oncology
  2. Mayo Clinic Comprehensive Cancer Center

Specialty Groups

  1. Spine Care
  2. Lung Cancer Program
  3. Brain Tumor Program
  4. Nuclear Medicine Therapy
  5. Early Onset and Hereditary GI Cancers Program
  6. Early-Onset Colorectal Cancer Group

Location

  1. Phoenix, Arizona

Languages

CantoneseChineseEnglish

Terence T. Sio, M.D., M.S., is Professor of Radiation Oncology and radiation oncologist who specializes in both X-ray based and proton radiotherapies. His main focuses are in gastrointestinal, lung, and brain cancers including brain metastasis treatments using stereotactic body radiotherapy (SBRT) and stereotactic radiosurgery (SRS). He has a strong interest in ion beam radiotherapies internationally.

Along with his other honors and awards, Dr. Sio is a peer-selected "Top Doc" in the Valley by the PHOENIX magazine (2025). He is board-certified by the American Board of Radiology, and uses ionizing radiation and proton beam therapies to treat malignant and also benign diseases.

  1. Acoustic neuroma
  2. Ampullary cancer
  3. Anal cancer
  4. Astrocytoma
  5. Brain cancer
  6. Brain metastasis
  7. Brain tumor
  8. Cholangiocarcinoma
  9. Chordoma
  10. Choroid plexus papilloma
  11. Colon cancer
  12. Ependymoma
  13. Esophageal cancer
  14. Gallbladder cancer
  15. Gastrointestinal stromal tumor
  16. Glioblastoma
  17. Glioma
  18. Hepatocellular carcinoma
  19. Liver cancer
  20. Lung cancer
  21. Meningioma
  22. Neuroendocrine tumor
  23. Neurofibroma
  24. Neurofibromatosis
  25. Oligodendroglioma
  26. Pancreatic cancer
  27. Pancreatic neuroendocrine tumor
  28. Pituitary tumor
  29. Rectal cancer
  30. Small bowel cancer
  31. Spinal cord tumor
  32. Spine tumor
  33. Stomach cancer
  1. Brain stereotactic radiosurgery
  2. Intensity-modulated radiation therapy
  3. Intraoperative radiation therapy
  4. Proton therapy
  5. Radiation therapy
  6. Stereotactic body radiotherapy
  7. Stereotactic radiosurgery
  • Central nervous system malignancies
  • Thoracic oncology including lung cancers
  • Gastrointestinal malignancies
  • Genitourinary malignancies
  • Proton beam radiotherapies with particular focus in scanning beam technologies
  • Patient outcome, symptom control, and quality-of-life research
  • Clinical trials
Phx

Phoenix, Arizona
  1. 2016
    Mayo Clinic Scholar - Visiting Assistant Professor (Radiation Oncology)Proton Therapy Center-Houston, MD Anderson Cancer Center
  2. 2011
    Internship - Internal MedicineUniversity of California San Francisco-Fresno
  3. 2010
    MMSc - Medical ScienceBrown University
  4. 2010
    MDBrown University
  5. 2006
    MS - Chemical Engineering Practice (M.S. CEP)Massachusetts Institute of Technology
  6. 2005
    BS - Chemical EngineeringMassachusetts Institute of Technology

Certifications

  1. 2016
    Radiation OncologyAmerican Board of Radiology

Awards and honors

  1. 2023
    2023 RO-ILS Radiation Oncology Safety Star AwardASTRO Quality Council, American Society for Radiation Oncology (ASTRO)
  2. 2022
    Mayo Clinic Experience Top Performing Provider Award (2021)Mayo Clinic
  3. 2020
    International Atomic Energy Agency (IAEA) FellowshipInternational Proton Beam Radiotherapy Educational Program and Training, Mayo Clinic Arizona
  4. 2015
    Roentgen Resident/Fellow Research AwardDepartment of Radiation Oncology
  5. 2010
    Alpha Omega Alpha Medical SocietyBrown Medical School

Professional memberships

  1. 2024 - present
    ChairSafety and Incident Learning System (SAILS), Department of Radiation Oncology
  2. 2024 - present
    ChairQuality Assurance Committee, Department of Radiation Oncology
  3. 2023 - present
    MemberRadiation Oncology Institute (ROI) Development Committee, American Society for Therapeutic Radiology and Oncology (ASTRO)
  4. 2023 - present
    Vice ChairLutetium Lu - 177 Dotatate Guidelines Working Group, Appropriateness Criteria, American College of Radiology (ACR)
  5. 2023 - present
    Co-Vice ChairPayer Relations Committee, Payer Relations Committee, American Society for Therapeutic Radiology and Oncology (ASTRO)
  6. 2023 - present
    Physician MemberIntensity Modulated Radiation Therapy (IMRT) Model Policy Working Group, Guidelines Committee, Quality Council
  7. 2022
    ReviewerProton Beam Therapy (PBT) Model Policy Working Group, Guidelines Committee, Quality Council
  8. 2022 - present
    Co-ChairSymptom Intervention-Health Disparities Working Group, Alliance for Clinical Trials in Oncology
  9. 2022 - present
    MemberMembership Committee, American Society for Therapeutic Radiology and Oncology (ASTRO)
  10. 2021 - present
    MemberAmerican College of Radiology (ACR)
  11. 2019 - present
    MemberNuclear Regulatory Commission (NRC) Subcommittee, American Society for Therapeutic Radiology and Oncology (ASTRO)
  12. 2019 - present
    MemberAmerican College of Radiation Oncology (ACRO)
  13. 2017 - present
    FacultyMayo Clinic Alix School of Medicine, Mayo Clinic in Arizona
  14. 2017 - 2020
    Member/ Abstract ReviewerAnnual Meeting, Gastrointestinal Malignancy Scientific Tract, American Society for Therapeutic Radiology and Oncology (ASTRO)
  15. 2016 - present
    MemberNRG Oncology
  16. 2016 - present
    MemberResearch Executive Committee (ROREC), Department of Radiation Oncology, Mayo Clinic in Arizona
  17. 2016 - 2021
    MemberAmerican Society of Clinical Oncology
  18. 2013 - 2015
    MemberARRO Global Health Subcommittee, American Society for Therapeutic Radiology and Oncology (ASTRO)
  19. 2011 - present
    MemberRare Cancer Network
  20. 2010 - present
    Lifetime MemberTau Beta Pi (TBP) Engineering Honor Society
  21. 2010 - present
    Lifetime MemberAlpha Omega Alpha Honor Medical Society