Modified radical mastectomy

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Last Name Initial: P

  1. Barbara A. Pockaj, M.D.

    Barbara A. Pockaj, M.D.

    1. Surgical Oncologist
    2. General Surgeon
    1. Phoenix, AZ
    Areas of focus:

    Mastectomy, Breast duct excision, Breast surgery, Breast cancer surgery, Nipple-sparing mastectomy, Sentinel lymph node... surgery, Modified radical mastectomy, Double mastectomy, Breast cancer, Fibroadenoma, Atypical hyperplasia of the breast, BRCA gene mutation, Breast cysts and lumps, Ductal carcinoma in situ, Male breast cancer, Triple-positive breast cancer, Metastatic breast cancer

Research Profiles

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Research

Mayo Clinic breast cancer surgeons regularly participate in research activities designed to improve care for people with breast cancer.

Some areas of research include:

  • Personalizing breast cancer treatments. Researchers are working on the latest treatments that take into account your genes and the particular genes of your cancer cells to offer precision medicine for breast cancer. Examples include discovering new biomarkers for targeted therapy and developing vaccines to prevent breast cancer from coming back.
  • Relieving pain after mastectomy. Pain control techniques before, during and after mastectomy can reduce the need for strong pain medicines during recovery.
  • Understanding how breast cancer develops. Researchers are working to understand the conditions under which breast cancer begins to develop. Research has focused on the unique microorganisms present within the breast, sometimes called the breast microbiome. This research may provide information that can help prevent breast cancer or find the most effective treatments.

Publications

See a list of publications about modified radical mastectomy by Mayo Clinic authors on PubMed, a service of the National Library of Medicine.

By Mayo Clinic Staff
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Aug. 15, 2026
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  1. Tyler DS, et al., eds. Diseases of the breast. In: Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice. 22nd ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed July 30, 2026.
  2. Nahabedian M. Overview of breast reconstruction. https://www.uptodate.com/contents/search. Accessed July 30, 2026.
  3. Kwong A, et al. Mastectomy. https://www.uptodate.com/contents/search. Accessed July 30, 2026.
  4. Breast cancer surgery. National Cancer Institute. https://www.cancer.gov/types/breast/treatment/surgery. Accessed July 30, 2026.
  5. Hagberg C. Perioperative care of the cancer patient: Breast procedures. In: Perioperative Care of the Cancer Patient. Elsevier; 2023. https://www.clinicalkey.com. Accessed July 30, 2026.
  6. Health Education & Content Services. MC5538-03: Medicines for breast cancer. Mayo Clinic; 2026.
  7. Health Education & Content Services. MC5538-04: Radiation therapy for breast cancer. Mayo Clinic; 2026.
  8. Health Education & Content Services. MC5538-05: Surgical treatments for breast cancer. Mayo Clinic; 2026.
  9. Mastectomy. Mayo Clinic. https://www.mayoclinic.org/tests-procedures/mastectomy/about/pac-20394670. Accessed July 30, 2026.
  10. Klimberg VS, et al., eds. General principles of mastectomy: From Halsted radical mastectomy and modified radical mastectomy to total (simple) mastectomy. In: Bland and Copeland's The Breast: Comprehensive Management of Benign and Malignant Diseases. 6th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Aug. 6, 2026.
  11. Klimberg VS, et al., eds. Modified radical mastectomy and simple mastectomy. In: Bland and Copeland's The Breast: Comprehensive Management of Benign and Malignant Diseases. 6th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Aug. 6, 2026.
  12. Margenthaler J. Technique of axillary lymph node dissection. https://www.uptodate.com/contents/search. Accessed Aug. 6, 2026.
  13. Breast cancer. American Cancer Society. https://www.cancer.org/cancer/types/breast-cancer.html. Accessed Aug. 6, 2026.
  14. Laws A, et al. Long-term patient-reported arm symptoms in breast cancer survivors. Annals of Surgical Oncology. 2024; doi:10.1245/s10434-023-14711-w.
  15. Axillary management for patients with in-situ and invasive breast cancer: A concise overview. American Society of Breast Surgeons. https://www.breastsurgeons.org/resources/statements/. Accessed Aug. 6, 2026.
  16. Technical considerations for axillary surgery in breast cancer patients. American Society of Breast Surgeons. https://www.breastsurgeons.org/resources/statements. Accessed Aug. 6, 2026.
  17. Preoperative management of patients treated with neoadjuvant systemic therapy. American Society of Breast Surgeons. https://www.breastsurgeons.org/resources/statements. Accessed Aug. 6, 2026.
  18. Jones C, et al. Evolution of operative technique for mastectomy. Surgical Clinics of North America. 2018; doi:10.1016/j.suc.2018.04.003.
  19. Park KU, et al. Sentinel lymph node biopsy in early-stage breast cancer: ASCO guideline update. Journal of Clinical Oncology. 2025; doi:10.1200/JCO-25-00099.
  20. Breast cancer. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/breast-cancer/symptoms-causes/syc-20352470. Accessed Aug. 6, 2026.
  21. Wang Q, et al. Immediate breast reconstruction with latissimus dorsi flap and implant: The innovation of flap design and transfer. Aesthetic Plastic Surgery. 2025; doi:10.1007/s00266-025-04740-z.
  22. Bryan AF, et al. Value of ambulatory modified radical mastectomy. Annals of Surgical Oncology. 2023; doi:10.1245/s10434-023-13588-z.
  23. Sikov WM, et al. General principles of neoadjuvant management of breast cancer. https://www.uptodate.com/contents/search. Accessed Aug. 9, 2026.
  24. Breast cancer surgery: What you need to know. National Breast Cancer Foundation. https://www.nationalbreastcancer.org/resources/breast-cancer-surgery-ebook. Accessed Aug. 9, 2026.
  25. Medical review (expert opinion), Aug. 10, 2026.

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