Chemotherapy for colon cancer

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Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments with related expertise

Areas that research this procedure

Research

Designated as a comprehensive cancer center by the National Cancer Institute, Mayo Clinic Comprehensive Cancer Center is defining new boundaries in colon cancer research.

Areas of research include:

  • Partnering with colleagues internationally to study whether shorter duration chemotherapy regimens are as effective as longer ones.
  • Developing nanoparticles as medicine delivery vehicles that can propel chemotherapy medicines to cancer cells.
  • Conducting or leading innovative clinical trials, such as chemotherapy regimens based on the genetic profile of a person's cancer cells.
  • Finding the best chemotherapy treatment for people after surgery by checking for any remaining cancer cells, called circulating tumor DNA, in the blood.

Publications

See a list of publications about colon cancer by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

By Mayo Clinic Staff

Chemotherapy for colon cancer care at Mayo Clinic

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AboutCare at Mayo Clinic
May 29, 2025
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  1. Colon cancer. National Comprehensive Cancer Network. https://www.nccn.org/guidelines/guidelines-detail?category=1&id=1428. Accessed Jan. 31, 2025.
  2. Morris VK, et al. Treatment of metastatic colorectal cancer: ASCO guideline. Journal of Clinical Oncology. 2023; doi:10.1200/JCO.22.01690.
  3. Baxter NN, et al. Adjuvant therapy for Stage II colon cancer: ASCO guideline update. Journal of Clinical Oncology. 2022; doi:10.1200/JCO.21.02538.
  4. DeVita VT Jr, et al., eds. Cancer of the colon. In: DeVita, Hellman, and Rosenberg's Cancer: Principles and Practice of Oncology. 12th ed. ProQuest Ebook Central. Wolters Kluwer; 2023. Accessed Feb. 4, 2025.
  5. Clark S, et al., eds. Chemotherapy and radiotherapy for colorectal cancer. In: Colorectal Surgery: A Companion to Specialist Surgical Practice. 7th ed. Elsevier; 2024. https://www.clinicalkey.com. Accessed Feb. 4, 2025.
  6. Colon cancer treatment (PDQ) — Health professional version. https://www.cancer.gov/types/colorectal/hp/colon-treatment-pdq. Accessed Feb. 4, 2025.
  7. Ou FS, et al. Changes in prescribing patterns in stage III colon cancer. Journal of the National Comprehensive Cancer Network. 2023; doi:10.6004/jnccn.2023.7028.
  8. Treating colorectal cancer. American Cancer Society. https://www.cancer.org/cancer/types/colon-rectal-cancer/treating.html. Accessed Jan. 30, 2025.
  9. Chemotherapy and you: Support for people with cancer. National Cancer Institute. https://www.cancer.gov/publications/patient-education/chemo-and-you. Accessed Feb. 22, 2025.
  10. Where you have chemotherapy. Cancer Research UK. https://www.cancerresearchuk.org/about-cancer/treatment/chemotherapy/how-you-have/where-you-have. Accessed March 5, 2025.
  11. Chemotherapy safety. American Cancer Society. https://www.cancer.org/cancer/managing-cancer/treatment-types/chemotherapy/chemotherapy-safety.html. Accessed March 5, 2025.
  12. Nimmagadda R. AllScripts EPSi. Mayo Clinic. Feb. 26, 2025.
  13. Vogel JD, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of colon cancer. Diseases of the Colon and Rectum. 2022; doi:10.1097/DCR.0000000000002323.
  14. Yang Y, et al. The optimal time of starting adjuvant chemotherapy after curative surgery in patients with colorectal cancer. BMC Cancer. 2023; doi:10.1186/s12885-023-10863-w.
  15. Overman MJ, et al. Overview of the management of primary colon cancer. https://www.uptodate.com/contents/search. Accessed March 6, 2025.

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Chemotherapy for colon cancer