Mayo Clinic's approach

  • Collaboration. Mayo Clinic's world-renowned urologic surgery teams include urologists and surgeons with training in specialized procedures for urinary symptoms. These specialists and other professionals work together to provide exactly the care you need. Your care is discussed among the team. Your appointments are scheduled in coordination, and test results are available quickly. The most highly specialized urology experts in the world all work together to determine what's best for you.
  • Experience. More than 850 people come to Mayo Clinic to have holmium laser prostate surgery each year.
  • Advanced technology. Mayo Clinic specialists are committed to providing the latest, minimally invasive treatment options for urinary symptoms caused by an enlarged prostate.
  • Research. Mayo Clinic researchers continue to refine holmium laser prostate surgery and other laser procedures while contributing to advances in laser technology and equipment.

Expertise and rankings

More than 850 people have holmium laser prostate surgery at Mayo Clinic every year. The surgery is technically challenging, and the most lasting results are achieved by skilled surgeons. Mayo Clinic urologic surgeons have the skills and training required to perform this specialized treatment.

Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Phoenix/Scottsdale, Arizona, and Mayo Clinic in Jacksonville, Florida, are ranked among the Best Hospitals for urology by U.S. News & World Report. Mayo Clinic Children's in Rochester is ranked the No. 1 hospital in Minnesota, and the five-state region of Iowa, Minnesota, North Dakota, South Dakota and Wisconsin, according to U.S. News & World Report's 2025-2026 "Best Children's Hospitals" rankings.

Learn more about Mayo Clinic's urology department's expertise and rankings.

Locations, travel and lodging

Mayo Clinic has major campuses in Phoenix and Scottsdale, Arizona; Jacksonville, Florida; and Rochester, Minnesota. The Mayo Clinic Health System has dozens of locations in several states.

For more information on visiting Mayo Clinic, choose your location below:

Costs and insurance

Mayo Clinic works with hundreds of insurance companies and is an in-network provider for millions of people.

In most cases, Mayo Clinic doesn't require a physician referral. Some insurers require referrals or may have additional requirements for certain medical care. All appointments are prioritized on the basis of medical need.

Learn more about appointments at Mayo Clinic.

Please contact your insurance company to verify medical coverage and to obtain any needed authorization prior to your visit. Often, your insurer's customer service number is printed on the back of your insurance card.

More information about billing and insurance:

Mayo Clinic in Arizona, Florida and Minnesota

Mayo Clinic Health System

Clinical trials

Explore Mayo Clinic studies of tests and procedures to help prevent, detect, treat or manage conditions.

Dec. 16, 2025
  1. AskMayoExpert. Benign prostatic hyperplasia. Mayo Clinic; 2023.
  2. Das AK, et al. Holmium laser enucleation of the prostate (HoLEP): Size-independent gold standard for surgical management of benign prostatic hyperplasia. Canadian Journal of Urology. 2020;27:44.
  3. McVary KT. Surgical treatment of benign prostatic hyperplasia. https://www.uptodate.com/contents/search. Accessed April 6, 2025.
  4. Helo S, et al. Minimally invasive and endoscopic management of benign prostatic hyperplasia. In: Campbell-Walsh-Wein Urology. 12th ed. Elsevier; 2021. https://www.clinicalkey.com. Accessed April 6, 2025.
  5. Abdelaziz A, et al. Contemporary trends of holmium laser enucleation of the prostate utilization in the United States: A comprehensive analysis using the National Surgical Quality Improvement Program Database (2011-2020). Journal of Endourology. 2024; doi:10.1089/end.2023.0612.
  6. Sandhu JS, et al. Management of lower urinary tract symptoms attributed to benign prostatic hyperplasia (BPH): AUA guideline amendment 2023. The Journal of Urology. 2024; doi:10.1097/JU.0000000000003698.
  7. Holmium laser enucleation of the prostate (HoLEP). The British Association of Urological Surgeons. https://www.baus.org.uk/patients/information_leaflets/177/holmium_laser_enucleation_of_the_prostate_holep. Accessed April 10, 2025.
  8. Holmium laser enucleation of the prostate. The Endourological Society. https://www.endourology.org/education-articles/holmium-laser-enucleation-of-the-prostate. Accessed April 10, 2025.
  9. Nimmagadda R. Allscripts EPSi. Mayo Clinic. March 25, 2025.
  10. Medical review (expert opinion). Mayo Clinic. May 8, 2025.

Holmium laser prostate surgery