Search Results 1-10 of 17318 for Apoptosis

  1. Apoptosis and the Response to Anti-Cancer Drugs - Anticancer Drug Action Laboratory - Mayo Clinic Research

    One pathway leading to apoptosis, the so-called extrinsic or death receptor pathway, involves tumor cell killing that is initiated by cytotoxic T lymphocytes ...

  2. Advancing understanding of CAR-T cell therapy for cancer - Mayo Clinic News Network

    ... apoptosis. I found similar results depleting a specific receptor involved in the apoptotic pathway. I also found tumor cells pre-treated with a monoclonal ...

  3. Claudia Manriquez Roman: CAR-T Cell Therapy for Cancer - Student Research - Mayo Clinic College of Medicine & Science

    ... apoptosis. I found similar results depleting a specific receptor involved in the apoptotic pathway. I also found tumor cells pre-treated with a monoclonal ...

  4. Inhibiting HDAC6 and HDAC1 upregulates RhoB with divergent downstream targets, BIM

    induced apoptosis should be employed. This study shows that the combination of either belinostat or vorinostat with paclitaxel may prove to be an effective ...

  5. Publications - Ruth Lupu, Ph.D. - Mayo Clinic

    ... apoptosis in pancreatic cancer. Neoplasia. 2025 Apr; 62:101143 Epub 2025 Feb 24. View PubMed; Lopez J, Llop-Hernandez A, Verdura S, Serrano-Hervas E, Martinez ...

  6. Gregory J. Gores, M.D. - Mayo Clinic Faculty Profiles

    Focus areas. Basic research. Role of death receptors in hepatocyte apoptosis; Carcinogenesis of biliary epithelia. Clinical research. Dr. Gores develops and ...

  7. Creation of a biomarker-augmented metastases score - Mayo Clinic

    ... apoptotic signaling molecule in tumor reactive CD8+ T cells ... This finding suggests that BIM has an important role in PD-L1-induced T cell apoptosis.

  8. Human Immunodeficiency Virus Lab: Andrew D. Badley - Research Projects

    HIV-1 infected T cells intrinsically resist apoptosis because HIV proteins alter expression of a wide variety of apoptosis regulatory proteins. Also ...

  9. Publications - Xia Zhou, M.B., Ph.D. - Mayo Clinic

    ... Apoptosis Protein 1 Signaling in Autosomal Dominant Polycystic Kidney Disease. ... Apoptosis. Biomolecules. 2024 Sep 26; 14 (10) Epub 2024 Sept 26. View ...

  10. Scott H. Kaufmann, M.D., Ph.D. - Mayo Clinic Faculty Profiles

    Many targeted agents induce the death process known as apoptosis. In this process, the pro-apoptotic proteins BAK and BAX breach the mitochondrial membrane to ...