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  1. Safety Study of SEA-CD40 in Cancer Patients - Mayo Clinic

    Different dose regimens will be evaluated. Different methods of administration may be evaluated. The pharmacokinetics, pharmacodynamic effects, biomarkers of ...

  2. Breast cancer - Doctors and departments - Mayo Clinic

    Learn about this common cancer, including information on prevention, symptoms, diagnosis and treatment.

  3. A Phase II Study Evaluating the Safety and Efficacy of Subcutaneous Plerixafor - Mayo Clinic

    About this study. This is a Phase II, open-label, two strata, multicenter, prospective study of plerixafor-mobilized HLA-identical sibling allografts in ...

  4. A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer - Mayo Clinic

    The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no ...

  5. Vorinostat, Temozolomide, or Bevacizumab in Combination with Radiation Therapy Followed by Bevacizumab and Temozolomide in Young Patients with Newly Diagnosed High-Grade Glioma - Mayo Clinic

    Vorinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as temozolomide, work in ...

  6. Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With Granulin Mutation - Mayo Clinic

    Study to Assess the Safety, Tolerability, and Pharmacodynamic (PD) Effects of FRM-0334 in Subjects With Prodromal to Moderate Frontotemporal Dementia With ...

  7. Sensorimotor Dysfunction in Achalasia - Clinical Trials

    About this study. This study is being done to assess the esophageal muscle (swallowing tube) in patients with and without achalasia to further understand ...

  8. An Investigational Immuno-therapy Study of Nivolumab, Compared to Placebo, in Patients With Bladder or Upper Urinary Tract Cancer, Following Surgery to Remove the Cancer - Mayo Clinic

    The purpose of this study is to determine the effectiveness and safety of Nivolumab compared to placebo in participants who have undergone radical surgery for ...

  9. Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder - Mayo Clinic

    This is a double-blind, sham controlled, multi-center study to confirm the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) for the ...

  10. The International Diabetes Closed Loop Trial DCLP4 - Mayo Clinic

    About this study. The purpose of this study is to compare the effectiveness and safety of an automated insulin delivery (AID) study system using a Model ...