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  1. Observational, Non-Interventional Study Supporting Validation of VO2Max Estimation Methods Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET) - Mayo Clinic

    Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices. Medical records research — uses historical ...

  2. A Study of the Safety and Effectiveness of NP001 for Patients with Amyotrophic Lateral Sclerosis (ALS) and Systemic Inflammation - Mayo Clinic

    The purpose of this study is to assess the safety and effectiveness of NP001 for the treatment of patients who have amyotrophic lateral sclerosis (ALS) and ...

  3. Study of ORIC-533 in Relapsed or Refractory Multiple Myeloma - Mayo Clinic

    About this study. The purpose of this study is to establish the Recommended Phase 2 Dose (RP2D), safety, pharmacokinetics (PK), pharmacodynamics (PD), ...

  4. The PCI Choice Trial: a Pilot Randomized Trial of a Decision Aid for Patients With Stable Coronary Artery Disease - Mayo Clinic

    About this study. Despite several large clinical trials clearly establishing that coronary revascularization (i.e. percutaneous coronary intervention - PCI) ...

  5. Validation of a Blood Assay for the Detection of BRAF Mutation Status in Patients with Metastatic Melanoma - Mayo Clinic

    The purpose of this study is to validate an internally developed assay for the detection of BRAF V600E mutations in cfDNA from the peripheral blood of patients ...

  6. Taselisib and Enzalutamide in Treating Patients With Androgen Receptor Positive Triple-Negative Metastatic Breast Cancer - Mayo Clinic

    Taselisib is a PI3K inhibitor. The PI3K pathway is involved is cancer growth. Androgen may cause the growth of tumor cells. Enzalutamide may stop the growth of ...

  7. Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia - Mayo Clinic

    About this study. The primary purpose of this dose-ranging study is to assess the safety and tolerability of 3 ascending doses of LX2006 gene therapy for ...

  8. A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001) - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness of MK-7240 compared to Placebo as assessed by the proportion of participants achieving clinical ...

  9. GA-68 PSMA-11 PET TO EVALUATE MALIGNANT GLIOMA RECURRENCE – A PILOT STUDY - Mayo Clinic

    The purpose of this study is to evaluate the utility of PSMA PET for differentiating recurrent glioma from radiation effect via pre-operative PSMA PET/CT in ...

  10. Metabolic Mapping and Cardiac Resynchronization - Mayo Clinic

    The purpose of this study is to gather information on the safety and effectiveness of cardiac resynchronization therapy (CRT) in patients who have mild heart ...