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  1. A Study of Pembrolizumab Alone or Combined with CC-486 for Patients with Platinum-Resistant Ovarian, Fallopian Tube, or Peritoneal Cancer - Mayo Clinic

    The purpose of the study is to determine the best dose of CC-486 (oral azacitidine) combined with pembrolizumab for the treatment of platinum-resistant ...

  2. A Study to Compare the Effectiveness and Safety of Emixustat Hydrochloride with Placebo to Treat Macular Atrophy Secondary to Stargadt Disease - Mayo Clinic

    The purpose of this study is to determine if emixustat hydrochloride (emixustat) reduces the rate of progression of macular atrophy (MA) compared to placebo in ...

  3. A Study to Determine Dose, Safety, and Efficacy of Durvalumab as Monotherapy and in Combination Therapy in Subjects With Lymphoma or Chronic Lymphocytic Leukemia - Mayo Clinic

    The study will have 3 parts: dose finding, dose confirmation, and dose expansion. Subjects receiving monotherapy may receive combination therapy or involved- ...

  4. A Clinical Trial for the Surgical Treatment of Elderly Distal Radius Fractures

    In the United States, over 300,000 individuals over age 65 suffer from distal radius fractures (DRFs) each year. Despite the frequency of this injury and ...

  5. Oral Pacritinib Versus Best Available Therapy to Treat Myelofibrosis With Thrombocytopenia - Mayo Clinic

    About this study. The primary hypothesis of the study is that treatment with either once-daily or twice-daily pacritinib results in a greater proportion of ...

  6. A Study to Predict Lung Cancer Using Noninvasive Biomarkers - Mayo Clinic

    The purpose of this study is to improve the efficiency of the diagnostic evaluation of patients with indeterminate pulmonary nodules. Participation eligibility.

  7. Study of EXE-346 Live Biotherapeutic to Reduce High Bowel Movement Frequency in Subjects With an IPAA (PROF) - Mayo Clinic

    The aim of this study is to assess the safety and preliminary efficacy of treatment with EXE-346, a live biotherapeutic, which may reduce bowel movement ...

  8. A Study to Investigate the Molecular Foundation of Spinal Tissue - Mayo Clinic

    The purpose of this study is to identify molecular mechanisms that control the rate of disc-dehydration, the effect of degeneration on surrounding bone and ...

  9. Genomic and Exposomic Hepatobiology: Konstantinos N. Lazaridis - Clinical trials, Clinical studies and Funding

    View clinical trials, clinical studies and funding information for Mayo Clinic's Genomic and Exposomic Hepatobiology Lab led by Konstantinos N. Lazaridis, ...

  10. High Sensitive Multichannel Non-Invasive Blood Pressure Monitor - Mayo Clinic

    The objective of this study is to obtain preliminary data to evaluate the accuracy of non-invasive blood pressure measurement in patients supported by ...