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  1. Envafolimab And Envafolimab With Ipilimumab In Patients With Undifferentiated Pleomorphic Sarcoma Or Myxofibrosarcoma - Mayo Clinic

    About this study. The purpose of this study is determine objective response rate (ORR) by RECIST 1.1 by blinded independent central review (BICR) of ...

  2. Monogenic Risk - eMERGE Genome Informed Risk Assessment - Mayo Clinic Research

    The eMERGE Genome Informed Risk Assessment study at Mayo Clinic estimates adult participants' risk of getting certain conditions from rare variants in a ...

  3. A Study to Evaluate the Safety and Effectiveness of the GORE® TAG® Thoracic Branch Endoprosthesis for Treating Lesions of the Aortic Arch and Chest Aorta - Mayo Clinic

    The purpose of this study is to determine whether the GORE® TAG® Thoracic Branch Endoprosthesis is safe and effective in treating lesions of the aortic arch and ...

  4. A Study of KRN23 in Adult Subjects with Tumor-Induced Osteomalacia or Epidermal Nevus Syndrome - Mayo Clinic

    The purpose of this study is to assess the effectiveness and safety of KRN23 administered to adult patients with inoperable tumor-induced osteomalacia or ...

  5. Open-label, Single Arm Trial of BI 695502 in Patients With Previously Untreated Metastatic Colorectal Cancer - Mayo Clinic

    As well as to evaluate the following efficacy parameters: Progression-free survival (PFS), objective response rate (proportion of patients with complete ...

  6. PH 1 Study to Evaluate Safety and Tolerability of XmAb14045 in Patients With CD123-expressing Hematologic Malignancies - Mayo Clinic

    About this study. Primary Objectives 1. To determine the safety and tolerability profile of weekly IV dosing of XmAb14045 2. To identify the first dose MTD/ ...

  7. A Study Comparing Recombinant Von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to Minimize Menorrhagia in Women with Type 1 Von Willebrand Disease - Mayo Clinic

    The purpose of this study is to compare recombinant Von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to minimize menorrhagia in women with Type 1 Von ...

  8. A Study to Evaluate the Safety and Effectiveness of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of OMS721 in patients with IgA nephropathy. The study will assess proteinuria by 24-hour ...

  9. A Study of MTI-301 in Patients with Advanced Malignancy - Mayo Clinic

    The purpose of this study is to assess and determine the maximum tolerated dose (MTD) for MTI-301. Participation eligibility. Participant eligibility includes ...

  10. A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia - Mayo Clinic

    The purpose of this study is to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Participants with Glanzmann ...