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  1. Phase 1/2, Open Label, Dose Escalation Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis - Mayo Clinic

    Dose escalation study to determine the maximum tolerated dose of NEOD001 in approximately 30 subjects with AL amyloidosis. Expansion phase to evaluate safety, ...

  2. Effect of TAK-954 on Gastrointestinal and Colonic Transit in Diabetic or Idiopathic Gastroparesis Participants - Mayo Clinic

    The purpose of this study is to evaluate the dose-dependent effects of TAK-954 on gastric emptying time of solids in participants with diabetic or idiopathic ...

  3. Oncolytic Adenovirus Coding for TNFa and IL2 (TILT-123) With Pembrolizumab or Pembrolizumab and Pegylated Liposomal Doxorubicin as Treatment for Ovarian Cancer. (PROTA) - Mayo Clinic

    The purpose of this study is to evaluate the safety [including dose-limiting toxicities (DLTs)] of the combination therapy of TILT-123 and pembrolizumab in ...

  4. Education and training - Biology of Aging and Age-Related Diseases Laboratory - Mayo Clinic Research

    Students · Biochemistry and molecular biology. · Biomedical engineering and physiology. · Clinical and translational science. · Immunology. · Molecular pharmacology ...

  5. Pilot Test of an Electronic Patient-Reported Outcome (ePRO) System to Monitor Post-Surgical Pain Self Management - Mayo Clinic

    The purpose of this study is to develop and pilot test an electronic patient-reported outcome (ePRO) monitoring and reporting tool for use in post-surgical pain ...

  6. Open Vs Robotic-Assisted Radical Cystectomy: A Randomized Trial - Mayo Clinic

    About this study. This is a multi-institutional, randomized trial evaluating oncologic, perioperative, and functional outcomes following two standard care ...

  7. Evaluating Real-World Outcomes for the Shape-Sensing Ion Endoluminal System - Mayo Clinic

    About this study. The purpose of this registry is to evaluate procedure characteristics and short and long-term patient outcomes following shape-sensing ...

  8. Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery - Mayo Clinic

    What is the incidence and etiology of bone overgrowth in protein versus other bone graft? Participation eligibility. Participant eligibility includes age, ...

  9. Classification of Breast Masses Using SAVE Method - Mayo Clinic

    About this study. The purpose of this research is to evaluate the efficacy of a new breast tissue assessment tool that provides new diagnostic information ...

  10. A Study to Evaluate Patient Reported Outcome Measures in Children with Eye Conditions - Mayo Clinic

    The objectives of this study are: To evaluate patient-reported quality of life and functional vision across the spectrum of pediatric eye conditions;; To assess ...