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  1. A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer - Mayo Clinic

    The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no ...

  2. A Study to Evaluate Androgen-Deprivation Therapy and Radiation Therapy in Treating Patients With Prostate Cancer - Mayo Clinic

    The purpose of this study is to compare the effects of hormone therapy (androgen deprivation) and radiation therapy to the prostate gland and seminal vesicles ...

  3. Using Induced-Pluripotent Stem Cells to Model Cancer Therapy-Related Adverse Events - Mayo Clinic

    The purpose of this study is to use patient blood cells to perform individualized in vitro modeling of cancer therapy-related toxicities. Participation ...

  4. Changes in Muscle, Body, Mechanics and Activity in Total Knee Arthroplasty - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. Analysis to Identify Biomarkers Associated With ADPKD - Mayo Clinic

    The purpose of this study is to collect biological samples (whole blood and saliva) to develop and validate a genotype assay for Autosomal Dominant Polycystic ...

  6. Tumor Heterogeneity of the Tumor Microenvironment in Malignant Pleural Mesothelioma (MPM) - Mayo Clinic

    Evaluate MPM tumor heterogeneity by determining the agreement of histology, molecular abnormalities, neo-antigen expression and immunological biomarkers between ...

  7. Cochlear Implantation Among Adults and Older Children with Unilateral or Asymmetric Hearing Loss - Mayo Clinic

    This is not a funded study. All costs are billed through insurance for reimbursement. There is an insurance approval process that we move through after a ...

  8. A Study to Investigate the Effectiveness and Safety of Fenfluramine Hydrochloride as an Adjunctive Therapy in Children and Adults With Lennox-Gastaut Syndrome - Mayo Clinic

    This is a two-part, multicenter, double-blind, parallel-group, placebo controlled study to evaluate the effect of ZX008 when used as adjunctive therapy for the ...

  9. Phase 1-2 Study of ADXS11-001 or MEDI4736 Alone or Combo In Cervical or HPV+ Head & Neck Cancer - Mayo Clinic

    About this study. Part A: (ADXS11-001 + MEDI4736 Combination Therapy) will determine the safety and tolerability of the combination and to identify a RP2D.

  10. Pazopanib Hydrochloride in Treating Patients With Advanced or Refractory Solid Tumors - Mayo Clinic

    Pazopanib hydrochloride may prevent the growth of new blood vessels that tumors need to grow. Studying samples of blood in the laboratory from patients ...