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  1. A Study of NGM282 When Given to Subjects with Functional Constipation and to Healthy Individuals - Mayo Clinic

    The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation ...

  2. A Study to Evaluate Durvalumab plus Topotecan or Lurbinectedin in Patients with Small Cell Lung Cancer - Mayo Clinic

    The purpose of this study is to evaluate whether the combination of durvalumab plus lurbinectedin can increase 6 month progression-free survival, in patients ...

  3. Faculty - Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery - Mayo Clinic Research

    The Mayo Clinic Kern Center for the Science of Health Care Delivery's multidisciplinary faculty guides research on the delivery of evidence-based, ...

  4. A Study Using Spinal Stimulation During Exercise in Patients with Heart Failure - Mayo Clinic

    About this study. The purpose of this study is to determine if epidural spinal cord stimulation can affect blood pressure control and blood vessel ...

  5. Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days - Mayo Clinic

    About this study. Evaluate the safety, tolerability, and efficacy of 28 days of treatment with ALLN-177 for reducing urinary oxalate excretion in patients ...

  6. Pharmacokinetics and Pharmacodynamic Biomarkers of Janus Kinase Inhibitor Therapy in Patients with Ulcerative Colitis (PROPHETIC Study) - Mayo Clinic

    Pharmacokinetics and Pharmacodynamic Biomarkers of Janus Kinase Inhibitor Therapy in Patients with Ulcerative Colitis (PROPHETIC Study) · Overview · Participation ...

  7. Care Optimization Through Patient and Hospital Engagement Clinical Trial for Heart Failure

    About this study. CONNECT-HF is a large-scale, pragmatic, cluster-randomized clinical trial to evaluate the effect of a customized, multifaceted, ...

  8. A Study Comparing BGB-3111 and Ibrutinib in Subjects With Waldenström's Macroglobulinemia (WM) - Mayo Clinic

    This study is to evaluate the safety, efficacy and clinical benefit of BGB-3111 vs ibrutinib in subjects with MYD88 Mutation Waldenström's Macroglobulinemia.

  9. The KAPP-Sen Tissue Mapping Center Collaborative - Mayo Clinic

    About this study. The purpose of the KAPP-Sen Tissue Mapping Center (TMC) Collaborative is an effort to characterize cellular senescence (cellular aging) in ...

  10. MAYO CLINIC DEPARTMENT OF NEUROLOGY BIOREPOSITORY

    About this study. The purpose of this study is to establish a repository consisting of clinical information, radiological data, serum, peripheral blood ...