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1. PTT-936, an Alpha Kinase 1 (ALPK1) Activator, Alone or in Combination with Anti-PD-1/L1 in Patients with Locally Advanced or Metastatic Solid Tumors - Mayo Clinic

   About this study. The primary objective of this study is to evaluate the safety and tolerability of a pharmacologically active dose (PAD) range of PTT-936, ...

2. A Study to Evaluate Placental Pathologies Using Ultrasound of the Human Placenta - Mayo Clinic

   The purpose of this study is to develop an ultrasound method to identify villitis of unknown etiology (VUE)-induced inflammation in the human placenta during ...

3. Return to Baseline Functional Status in Elderly Women Undergoing Pelvic Organ Prolapse Surgery - Mayo Clinic

   About this study. Our primary aim is to determine the rate of return to baseline functional status 3 months post-operative pelvic organ prolapse surgery in ...

4. Testing the Addition of the Drug Atezolizumab to the Usual Radiation Treatment for Patients With Early Non-small Cell Lung Cancer - Mayo Clinic

   This trial studies how well atezolizumab added to the usual radiation therapy works in treating patients with stage I-IIA non-small cell lung cancer.

5. A Study of Using Botox to Decrease the Rate of Ventral Hernias Caused by Damage Control Laparotomy - Mayo Clinic

   The purpose of this study is to compare the rate of developing a ventral hernia after a damage control laparotomy between patients who had Botox induced ...

6. Impact of Neoadjuvant Chemotherapy on the Peripheral Blood Immune Phenotype in Operable Breast Cancer, the ENHANCE Study - Mayo Clinic

   About this study. The purposes of this study are to evaluate whether pre-NAC peripheral blood immune phenotypes (defined by mass cytometry) are associated ...

7. GEN1046 in Combination With Anticancer Agents for the Treatment of Advanced Endometrial Cancer - Mayo Clinic

   The purpose of this study is to evaluate the antitumor activity of GEN1046 in combination with anticancer therapy in subjects with advanced endometrial cancer.

8. A Study of Secukinumab Compared to Ustekinumab for Treatment of Patients with Plaque Psoriasis - Mayo Clinic

   The purpose of this study is to assess the long-term safety, tolerability, and effectiveness of secukinumab over ustekinumab for the treatment of patients who ...

9. A Study of Transthoracic Echocardographic Assessment for Pulmonary Artery Pressure Measurements - Mayo Clinic

   The purpose of this study is to improve the noninvasive assessment of right atrial pressures by correlating tradiational echo findings with other echo ...

10. A Study of Budesonide Suspension in Adolescents and Adults with Eosinophilic Esophagitis Measuring Histologic Response and Decreased Dysphagia - Mayo Clinic

    A study of the effectiveness of oral Budesonide suspension in adolescents and adults with eosinophilic esophagitis measuring the histologic response and ...