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  1. DS-8201a in Human Epidermal Growth Factor Receptor2 (HER2)-Expressing Colorectal Cancer (DESTINY-CRC01) - Mayo Clinic

    The main objective of this study is to test the safety and effectiveness of DS-8201a for participants with HER2-expressing advanced colorectal cancer.

  2. Faculty - Women's Health Research Center - Mayo Clinic Research

    Enninga, Elizabeth Ann L. Ph.D. Assistant Professor of Immunology; Assistant Professor of Obstetrics and Gynecology; Publications · Ertekin-Taner, Nilufer M.D., ...

  3. A Phase 1b/2 Safety and Tolerability of MEDI6469 in Combination With Therapeutic Immune Agents or Monoclonal Antibodies - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. A Study to Estimate the Clinical Benefit of REGN2810 for Patients with Advanced Squamous Cell Skin Cancer

    The purpose of this study is to estimate the clinical benefit of REGN2810 for patients who have metastatic (in lymph nodes or distant) squamous cell skin cancer ...

  5. Phase 1/2, Open Label, Dose Escalation Study of NEOD001 in Subjects With Light Chain (AL) Amyloidosis - Mayo Clinic

    Dose escalation study to determine the maximum tolerated dose of NEOD001 in approximately 30 subjects with AL amyloidosis. Expansion phase to evaluate safety, ...

  6. An Extension Study to Evaluate the Long-Term Safety and Tolerability of NEOD001 for Treatment of People with Light Chain Amyloidosis - Mayo Clinic

    The purpose of this study is to provide additional treatment with NEOD001 and evaluate long term safety and tolerability for patients wih light chain ...

  7. Culture and Language Neutral Computerized Cognitive Screening Test among Latinos - Mayo Clinic

    The Latino population has a sedentary lifestyle with associated common health problems such as diabetes, obesity, cardiometabolic disorders and hypertension ...

  8. Dose Escalation Study Investigating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of ASP2215 in Patients With Relapsed or Refractory Acute Myeloid Leukemia - Mayo Clinic

    The objective of this study is to assess the safety and tolerability, including the maximum tolerated dose, of ASP2215 in subjects with relapsed or treatment- ...

  9. First-in-Human Study of KO-947 in Non-Hematological Malignancies - Mayo Clinic

    If an MTD cannot be identified, a recommended phase 2 dose (RP2D) will be determined. In addition, two tumor specific extension cohorts may be conducted to ...

  10. Active Removal of IntraCerebral Hematoma Via Active Irrigation - Mayo Clinic

    Study evaluating if active irrigation by IRRAflow® with infusion of tPA will reduce the time needed for clearance of intracerebral and intraventricular ...