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  1. Grit as a Predictor of Outcomes in Transcatheter Valvular Therapeutic Candidates - Mayo Clinic

    About this study. The purpose of this study is to provide a survey to prospective candidates undergoing transcatheter valve replacement or repair at two ...

  2. A Registry of Childhood Sjogren Disease - Clinical Trials

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. A Study of NGM282 When Given to Subjects with Functional Constipation and to Healthy Individuals - Mayo Clinic

    The purpose of this study is to determine the effect of NGM282 on colonic transit, bile acid homeostasis, and fecal fat in subjects with functional constipation ...

  4. A Study to Evaluate the Effectiveness and Safety of Pemigatinib Versus Chemotherapy in Unresectable or Metastatic Cholangiocarcinoma - Mayo Clinic

    The purpose of this study is to evaluate the effectiveness and safety of pemigatinib versus gemcitabine plus cisplatin chemotherapy in first-line treatment of ...

  5. A Study of the Safety and Effectiveness of Combined Toca 511 and Toca FC for Patients Having Removal Surgery for Recurring Glioblastoma or Anaaplastic Astrocytoma - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  6. Bortezomib or Carfilzomib With Lenalidomide and Dexamethasone in Treating Patients With Newly Diagnosed Multiple Myeloma - Mayo Clinic

    About this study. This randomized phase III trial studies bortezomib, lenalidomide, and dexamethasone to see how well it works compared to carfilzomib, ...

  7. A Study of Application of Clonal Analysis to Study Flow Sorted Clinical Samples from Patients with Advanced Solid Tumors - Mayo Clinic

    This study is being done so researchers can study the genetics of your tumor to better understand how the tumor grows and spreads and collect a blood sample to ...

  8. A Study of the Outcomes of Natalizumab plus Standard Steroid Treatment for High Risk Acute Graft-Versus-Host Disease - Mayo Clinic

    GVHD is the most common serious complication, after bone marrow transplant. GVHD occurs when the donor cells (the graft), treat the recipient's body as "foreign ...

  9. Retrospective Study of Adult Acute Myeloid Leukemia and the Impact on Clinical Characteristics & Outcomes After Therapy

    The purpose of this study is to perform a retrospective review of adult patients diagnosed with AML at all 3 Mayo Clinic sites over the past 25 years in order ...

  10. Epsilon Aminocaproic Acid (EACA) for the Reduction of Blood Loss in Total Hip Arthroplasty (THA) - Mayo Clinic

    About this study. You are being asked to take part in this research study because you are scheduled to have total hip replacement (arthroplasty) surgery.