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  1. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation - Mayo Clinic

    About this study. The purpose of this study is to evaluate the effect of macitentan 10 mg on pulmonary vascular resistance as compared to placebo in ...

  2. A Study to Assess Changes of Heart Function and Aortic Stiffness in Relation to Intra-dialytic Hypotension - Mayo Clinic

    About this study. Our aim is to analyze changes in global and/or regional myocardial mechanics of the left and right ventricle before and after hemodialysis ...

  3. Genetic Testing with Family History of Pancreatic Cancer - Mayo Clinic

    The purpose of this study is perform HOUSES index analysis on 500 patients with a first-degree relative diagnosed with pancreatic cancer to see if there is a ...

  4. OTC Deficiency Study - Clinical Trials

    About this study. The objectives of this study are to perform genomic testing and trio analysis on specimens from three deceased patients with partial OTC ...

  5. A Study to Determine the Effect of Endogenous Glucagon-Like Peptide-1 on Active Intestinal Glucose Transport and Intestinal Permeability - Mayo Clinic

    The purpose of this study is to determine the effect of endogenous glucagon-like peptide-1 on active intestinal glucose transport and on intestinal permeability ...

  6. Simtuzumab (GS-6624) in the Treatment of Cirrhosis Due to NASH - Mayo Clinic

    This study is to evaluate the safety and efficacy of simtuzumab (GS-6624) in adults with compensated cirrhosis due to Non-Alcoholic Steatohepatitis (NASH). It ...

  7. The Effects of Aortic Valve Replacement on Sleep Disordered Breathing, Heart Rate Variability and Ventricular Ectopy Burden in Patients with Severe Aortic Stenosis - Mayo Clinic

    Our overall goal is to determine whether the AVR improves SDB where present and sleep profiles (including sleepiness symptoms, quality of life and hypoxia).

  8. A Study of Gluten Intolerance in Patients with Diarrhea Predominant Irritable Bowel Syndrome - Mayo Clinic

    The purpose of this study is to test gluten supplementation for four weeks, to see if it increases small intestinal permeability and accelerates colonic transit ...

  9. Edwards Cardioband™ Tricuspid Valve Reconstruction System Early Feasibility Study - Mayo Clinic

    About this study. The purpose of this early feasibility study is to assess the safety and performance of the Edwards Cardioband™ FIT Valve Repair System.

  10. Pazopanib in Treating Patients with Metastatic Non-Clear Cell Kidney Cancer - Mayo Clinic

    Pazopanib hydrochloride may also stop the growth of kidney cancer by blocking blood flow to the tumor. Participation eligibility. Participant eligibility ...