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  1. PORtopulmonary Hypertension Treatment wIth maCitentan ─ a randOmized Clinical Trial

    24-week study to evaluate the efficacy and safety of macitentan for the treatment of portopulmonary hypertension. Participation eligibility. Participant ...

  2. A Study to Assess the Safety, Tolerability and Effectiveness of LJN452 for Treating Patients who have Primary Biliary Cholangitis - Mayo Clinic

    The purpose of this study is to assess the safety, tolerability and effectiveness of LJN452 for the treatment of patients who have primary biliary cholangitis.

  3. A Phase 1/2 Study to Evaluate MEDI4736 - Clinical Trials

    This is a multicenter, open-label, first-time-in-human study with a standard 3+3 dose-escalation phase in subjects with advanced solid tumors followed by an ...

  4. A Study of Advanced Magnetic Resonance Technology Design Toward Enhancing Its Value - Mayo Clinic

    About this study. The purpose of this study is to develop and test a wide range of software, all designed to operate an MRI scanner more efficiently - to ...

  5. Evaluate the Effect of ALLN-177 in Reducing Urinary Oxalate in Patients With Secondary Hyperoxaluria and Kidney Stones Over 28 Days - Mayo Clinic

    About this study. Evaluate the safety, tolerability, and efficacy of 28 days of treatment with ALLN-177 for reducing urinary oxalate excretion in patients ...

  6. Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma - Mayo Clinic

    The purpose of this study is to assess the safety, tolerability and preliminary efficacy of nal-IRI in combination with 5-FU/LV and oxaliplatin in patients not ...

  7. Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma - Mayo Clinic

    The purpose of this study is to determine if open surgical resection is superior to thoracoscopic resection for thoracic event-free survival (tEFS) in patients ...

  8. Registry of Patients Prescribed Anticoagulation - Mayo Clinic

    We also want to compare efficacy and safety of novel anticoagulants to "traditional" anticoagulants such as warfarin and low molecular weight heparin (LMWH) and ...

  9. Study to Evaluate the Effects of RM-131 in Patients With Chronic Constipation - Mayo Clinic

    About this study. The purpose of this study is to evaluate safety and tolerability as well as the effects of RM-131 on colonic motor and sensory effects in ...

  10. Review of the Safety and Effectiveness of the THERMOCOOL SMARTTOUCH® SF Catheter Evaluated for Treating Symptomatic PersistenT AF (PRECEPT) - Mayo Clinic

    This is a prospective, multicenter, non-randomized clinical evaluation utilizing the THERMOCOOL SMARTTOUCH® SF catheter compared to a predetermined performance ...