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  1. Phase 1 Study of PLX7486 as Single Agent in Patients With Advanced Solid Tumors - Mayo Clinic

    About this study. The objective of this study is to determine the safety, pharmacokinetics, maximum tolerated dose/recommended Phase 2 dose, and efficacy of ...

  2. A Study to Evaluate Convalescent Plasma to Stem Coronavirus - Mayo Clinic

    The purpose of this study is to assess the effectiveness and safety of Human coronavirus immune plasma (HCIP) to reduce the risk of hospitalization or death, ...

  3. Induction of Oral Tolerance During Early Life - Mayo Clinic Research

    The Early Life Immune Responses Lab of Kathryn A. Knoop, Ph.D., at Mayo Clinic, studies tolerance to oral antigens and prevention of antigen translocation ...

  4. Aurinia Renal Response in Active Lupus With Voclosporin - Mayo Clinic

    The purpose of this study is to assess the efficacy of voclosporin compared with placebo in achieving renal response after 52 weeks of therapy in subjects with ...

  5. A Study of APG-2575 Alone or in Combination with Other Therapeutic Agents to Treat Relapsed and/or Refractory Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL) - Mayo Clinic

    The purpose of this study is to assess the safety and tolerability, identify dose-limiting toxicities (DLT) and determine the maximum tolerated dose (MTD) / ...

  6. A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir and Dasabuvir in Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection and Cirrhosis - Mayo Clinic

    A Study to Evaluate the Safety and Efficacy of Ombitasvir/ABT-450/Ritonavir and Dasabuvir in Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection ...

  7. A Study Evaluating Efruxifermin in Subjects with Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis - Mayo Clinic

    The purpose of this study is to evaluate efruxifermin (EFX) in subjects with non-cirrhotic NASH/MASH and fibrosis stage 2 or 3 (F2 or F3). Participation ...

  8. A Study to Assess Whether Macitentan Delays Disease Progression in Children With Pulmonary Arterial Hypertension (PAH) - Mayo Clinic

    This is a prospective, multicenter, open-label, randomized, controlled, parallel group, group-sequential, event-driven Phase 3 study to evaluate efficacy, ...

  9. A Study of Alcohol Consumption History and Disease Free Survival in Stage III Colon Cancer Patients - Mayo Clinic

    The purpose of this study is to assess the relationship between lifetime and recent alcohol consumption history and disease free survival in a population of ...

  10. Study of Intralesional Cemiplimab in Adult Patients With Early Stage Cutaneous Squamous Cell Carcinoma - Mayo Clinic

    About this study. This study will test a study drug called cemiplimab to see if it can help treat early-stage cutaneous squamous cell carcinoma (CSCC), ...