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  1. A Study of the Safety and Effectiveness of NEOD001 for Treating Previously Treated Patients with Persistent Cardiac Dysfunction Related to Light Chain Amyloidosis - Mayo Clinic

    About this study. The purpose of this study is to assess the effectiveness and safety of NEOD001 administered intravenously in adults with light chain ...

  2. Study of Nanoliposomal Irinotecan (Nal-IRI)-Containing Regimens in Patients With Previously Untreated, Metastatic Pancreatic Adenocarcinoma - Mayo Clinic

    The purpose of this study is to assess the safety, tolerability and preliminary efficacy of nal-IRI in combination with 5-FU/LV and oxaliplatin in patients not ...

  3. Alumni - Brain and Systemic Aging: Marissa J. Schafer - Mayo Clinic Research

    Jair Machado Espindola Netto, Ph.D. 2023-2025; Principle Research Technologist. Merve Atik, M.D.; 2024; Student. Paul Gomez, B.S.; 2022-2024 ...

  4. Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors - Mayo Clinic

    This study will also learn more about how the combination of these two investigational drugs may work for patients with certain cancers (specifically metastatic ...

  5. A Study Using the New TLR8 Agonist VTX-2337 and Cyclophosphamide in Treating Patients with Metastatic, Persistent, Recurrent, or Progressive Solid Tumors - Mayo Clinic

    About this study. This phase Ib trial studies the best way of TLR8 Agonist VTX-2337 and cyclophosphamide in treating patients with a solid tumor that has ...

  6. Cancer Biology and Translational Research - Collaborators

    The Cancer Biology and Translational Research Lab at Mayo Clinic collaborates with investigators worldwide who share expertise in oncogenomics and novel ...

  7. Trials Evaluating Oral Full-Spectrum Microbiota™ (CP101) in Subjects with Recurrence of Clostridium difficile Infection - Mayo Clinic

    The purpose of this study is to evaluate the safety and effectiveness of CP101 treatment in adults who had a Clostridum difficile Infection (CDI) recurrence ...

  8. A Study to Evaluate Chemotherapy-Induced Nausea in Breast Cancer Patients - Mayo Clinic

    The long-term goal of this study is to alleviate the occurrence of CIN and fatigue and to improve chemotherapy treatment outcomes. The identification of ...

  9. Efficacy, Safety, and Tolerability of Oral Full-Spectrum Microbiota® (CP101) in Subjects with Recurrence of Clostridium difficile Infection (PRISM3) - Mayo Clinic

    Efficacy, Safety, and Tolerability of Oral Full-Spectrum Microbiota® (CP101) in Subjects with Recurrence of Clostridium difficile Infection (PRISM3) · Overview.

  10. A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors - Mayo Clinic

    Phase 2 only: To assess preliminary antitumor activity by overall response rate (ORR) as measured by Response Evaluation Criteria in Solid Tumors (RECIST) v1.1 ...