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1. Assessment of Coronary Plaque Composition Using Optical Coherence Tomography - Mayo Clinic

   About this study. The investigators hypothesis is that local activation of the endogenous Lp-PLA2 plays an integral role in early atherosclerosis, ...

2. A Study Comparing Recombinant Von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to Minimize Menorrhagia in Women with Type 1 Von Willebrand Disease - Mayo Clinic

   The purpose of this study is to compare recombinant Von Willebrand Factor (rVWF) vs. Tranexamic Acid (TA) to minimize menorrhagia in women with Type 1 Von ...

3. Avatrombopag for the Treatment of Thrombocytopenia in Adults Scheduled for a Surgical Procedure - Mayo Clinic

   About this study. Phase 3b open-label, multicenter study to evaluate the safety and efficacy of avatrombopag in subjects with thrombocytopenia scheduled for ...

4. Trimethoprim-sulfamethoxazole Graded Administration in Oncology, Hematopoietic Stem Cell Transplant, and Solid Organ Transplant Patients with a History of Sulfonamide Allergy - Mayo Clinic

   Trimethoprim-sulfamethoxazole Graded Administration in Oncology, Hematopoietic Stem Cell Transplant, and Solid Organ Transplant Patients with a History of ...

5. Reflex Responses to Intermittent Hypoxia in Humans - Mayo Clinic

   Sleep apnea is the most common form of sleep disordered breathing and patients with sleep apnea exhibit persistent activation of the sympathetic nervous system.

6. A Study of Patterns of Contrast Deposits in the Brains of Patients with a History of Gadolinium Contrast Exposure - Mayo Clinic

   The purpose of this study is to identify the area patterns of deposits in the brains of subjects who have a prior history of gadolinium contrast exposure. These ...

7. Validation of Gene Expression Markers of Renal Allograft Functional Decline - Mayo Clinic

   About this study. Researchers would like to see if it is possible to predict which transplanted kidneys will do better long term based on the gene ...

8. ECOSPOR III - SER-109 Versus Placebo in the Treatment of Adults With Recurrent Clostridium Difficile Infection - Mayo Clinic

   About this study. Subjects will receive an oral dose of SER-109 in 4 capsules once daily for 3 consecutive days in Treatment Group I or matching placebo ...

9. Study of Safety and Tolerability of VLX600, an Iron Chelator, in Patients with Refractory Advanced Solid Tumors - Mayo Clinic

   The purpose of this study is to evaluate the safety and tolerability of the investigational drug VLX600 in patients with refractory advanced solid tumors.

10. Comparison of Operation to Monitoring With/Without Endocrine Therapy For Low Risk DCIS - Mayo Clinic

    This study looks at the risks and benefits of active surveillance (AS) compared to guideline concordant care (GCC) in the setting of a pragmatic prospective ...