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  1. Safety Study of Mocetinostat in Combination With Azacitidine in Subjects With MDS - Mayo Clinic

    Mocetinostat is an orally administered histone deacetylase (HDAC) inhibitor. Azacitidine is a hypomethylating agent (HMA) used to treat MDS. In this study, ...

  2. A Phase I Study of MSB2311 in Advanced Solid Tumors - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  3. A Study to Evaluate the Effectiveness and Safety of Ralinepag To Improve Treatment Outcomes in Peripheral Arterial Hypertension (PAH) Patients - Mayo Clinic

    About this study. To evaluate the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific ...

  4. A Study to Test How Muscle Tissue Differs Between People - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  5. A Study of Diabetes-associated Epigenomic Signatures in Humans - Mayo Clinic

    About this study. The obectives of this study are to identify insulin resistance (IR)-specific chromatin signatures in mature adipocytes and myotubes, ...

  6. Defibrotide for Patients with Hepatic Veno-occlusive Disease: A Treatment IND Study - Mayo Clinic

    Single arm, open-label study to provide Defibrotide to patients diagnosed with VOD. Defibrotide is no longer available though the Emergency Use IND mechanism ( ...

  7. Genomic and Environmental Basis of Imperforate Anus - Mayo Clinic

    About this study. The study aims are to develop a consent-based IRB proposal that will enroll newborns who have imperforate anus. The proposal will include ...

  8. A Study to Create a Registry for Patients at High-Risk for Pancreatic Cancer - Mayo Clinic

    This study aims to facilitate discovery and validation of tests for early detection in subjects at high risk for pancreatic ductal adenocarcinoma (PDAC). and to ...

  9. Letrozole in Treating Postmenopausal Women Who Have Received Hormone Therapy for Hormone Receptor-Positive Breast Cancer - Mayo Clinic

    About this study. RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone therapy using letrozole may fight breast cancer by lowering the ...

  10. Voice Analytics for Predicting the Physical Health of Patients - Mayo Clinic

    About this study. We aim to test the hypothesis that the quality of human voice can be analyzed by multimodal machine learning approaches to assess overall ...