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1. Atezolizumab With Or Without Cobimetinib In Treating Patients With Metastatic Bile Duct Cancer That Cannot Be Removed By Surgery Or Gallbladder Cancer - Mayo Clinic

   Monoclonal antibodies, such as atezolizumab, may interfere with the ability of tumor cells to grow and spread. Cobimetinib may stop the growth of tumor cells by ...

2. Study To Investigate LP352 In Subjects With Developmental And Epileptic Encephalopathies (PACIFIC) - Mayo Clinic

   About this study. The primary objective of this study is to investigate the safety, tolerability, and effectiveness of multiple doses of LP352 in adult ...

3. A Study To Learn About The Study Medicine Called PF-08634404 In Combination With Chemotherapy In Adult Participants With Metastatic Colorectal Cancer - Mayo Clinic

   The purpose of this study is to learn more about a new medicine called PF-08634404, and how well it works in people with cancer of the colon or rectum (CRC)).

4. A Study Of The Safety And Tolerability Of JNJ-55920839, Either As A Single Ascending Dose In Healthy Individuals Or As Multiple Doses For Patients Who Have Mild To Moderate Systemic Lupus Erythematosus - Mayo Clinic

   A Study Of The Safety And Tolerability Of JNJ-55920839, Either As A Single Ascending Dose In Healthy Individuals Or As Multiple Doses For Patients Who Have Mild ...

5. A Study Comparing BGB-3111 And Ibrutinib In Subjects With Waldenström's Macroglobulinemia (WM) - Mayo Clinic

   This study is to evaluate the safety, efficacy and clinical benefit of BGB-3111 vs ibrutinib in subjects with MYD88 Mutation Waldenström's Macroglobulinemia.

6. A Study To Evaluate Intravenous Iloprost In Subjects With Symptomatic Raynaud's Phenomenon Secondary To Systemic Sclerosis - Mayo Clinic

   The purpose of this study is to evaluate the safety and effieativeness of iloprost on the frequency of and relief from symptomatic digital ischemic episodes in ...

7. A Phase I Study Of MSB2311 In Advanced Solid Tumors - Mayo Clinic

   This is a phase I study to determine the safety and toxicity, PK/PD, immunogenicity, biomarkers, anti-tumor activity and establish a preliminary recommended ...

8. Inpatient, Dose-Ranging Study Of Staccato Alprazolam In Epilepsy With Predictable Seizure Pattern - Mayo Clinic

   These subjects have an established diagnosis of focal or generalized epilepsy with a documented history of predictable seizure episodes. This is an in-patient ...

9. A Study To Evaluate Tazemetostat And Pembrolizumab To Treat Advanced Urothelial Carcinoma - Mayo Clinic

   Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

10. Randomized Study To Assess The Safety, Pharmacokinetics/Dynamics Of DS-1040b In Subjects With Acute Submassive Pulmonary Embolism - Mayo Clinic

    About this study. This is a Phase 1b, double-blind (Principal Investigators, study subjects, Sponsor, Academic Research Organization ARO and Clinical ...