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1. Nilotinib and Combination Chemotherapy in Treating Patients with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia or Blastic Phase Chronic Myelogenous Leukemia - Mayo Clinic

   About this study. In this study researchers want to find out more about the side effects of a new drug for Philadelphia chromosome-positive (Ph+) acute ...

2. A Study To Evaluate The Combination Of Binimetinib And Palbociclib In Treating Patients With KRAS And NRAS Mutant Metastatic Or Unresectable Colorectal Cancer - Mayo Clinic

   The purose of this study is to determine how well binimetinib and palbociclib work compared to TAS-102 in treating patients with KRAS and NRAS mutation positive ...

3. Study Of Encorafenib + Cetuximab Plus Or Minus Binimetinib Vs. Irinotecan/Cetuximab Or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With A Safety Lead-in Of Encorafenib + Binimetinib + Cetuximab In Patients With BRAF V600E-mutant Metastatic Colorectal Cancer - Mayo Clinic

   Study Of Encorafenib + Cetuximab Plus Or Minus Binimetinib Vs. Irinotecan/Cetuximab Or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/ ...

4. Placebo Controlled Study Of VS-6063 In Subjects With Malignant Pleural Mesothelioma - Mayo Clinic

   Prior to entry and randomization to the study, each subject must have tumor Merlin status(high or low) established by immunohistochemistry performed at a ...

5. Micra Transcatheter Pacing Study - Clinical Trials

   About this study. The purpose of this clinical study is to evaluate the safety and efficacy of the Micra Transcatheter Pacing System and to assess long term ...

6. ASPEN-09: A Study Of Evorpacept In Combination With Anti-cancer Therapies In Advanced / Metastatic Malignancies - Mayo Clinic

   * Metastatic HER2+ breast cancer (MBC) - single-arm substudy evaluating the efficacy, safety, and tolerability of evorpacept in combination with trastuzumab and ...

7. Study Of 177Lu-PSMA-617 In Metastatic Castrate-Resistant Prostate Cancer - Mayo Clinic

   The purpose of this study is to compare overall survival (OS) in patients with progressive PSMA-positive mCRPC who receive 177Lu-PSMA-617 in addition to best ...

8. A Study To Evaluate Ribociclib Plus Letrozole To Treat Cancer Of The Ovary, Fallopian Tube Or Peritoneum - Mayo Clinic

   The purpose of this study is to evaluate the response to treatment with Ribociclib and Letrozole in patients with low-grade serous cancer of the ovary, ...

9. Study To Investigate The Safety And Effectiveness Of Two Doses Of The Antibody Drug GSK2857916 In Relapsed/Refractory Multiple Myeloma Patients - Mayo Clinic

   The purpose of this study is to investigate the safety and effectiveness of two doses of the antibody drug GSK2857916 in multiple myeloma patients who had 3 or ...

10. A Study Of KRN23 In Adult Subjects With Tumor-Induced Osteomalacia Or Epidermal Nevus Syndrome - Mayo Clinic

    The purpose of this study is to assess the effectiveness and safety of KRN23 administered to adult patients with inoperable tumor-induced osteomalacia or ...