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  1. Polyphenon E in Treating Patients with High-Risk of Colorectal Cancer - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  2. A Study to Evaluate Injectafer® as Treatment for Heart Failure with Iron Deficiency - Mayo Clinic

    The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to ...

  3. Cisplatin, Intensity-Modulated Radiation Therapy, and Pembrolizumab in Treating Patients With Stage III-IV Head and Neck Squamous Cell Carcinoma - Mayo Clinic

    Monoclonal antibodies, such as pembrolizumab, may block tumor growth in different ways by targeting certain cells. Drugs used in chemotherapy, such as cisplatin ...

  4. A Study of Biomechanics of Dislocating Hips and Asymptomatic Non-dislocating Hips - Mayo Clinic

    About this study. The primary objective of this study is to determine whether the functional cup orientation for dislocating hips differs from the ...

  5. Inotropes: Intent and Result of Elective Initiation During Heart Failure Hospitalization - Mayo Clinic

    About this study. The purpose of this study is to identify clinical demographics of patients initiated on inotropes during a heart failure admission and ...

  6. Advertising and Sponsorship - Mayo Clinic

    Corporate image advertising or corporate sponsorship; Over-the-counter medications approved by the Food and Drug Administration (FDA); Prescription drugs ...

  7. Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies - Mayo Clinic

    About this study. Primary Objective: Phase 1: To determine the maximum tolerated dose (MTD)/maximum administered dose (MAD) of SAR650984 (Isatuximab).

  8. A Study of Abdominal Wall Muscle Contractions in Healthy and Disordered Defecation - Mayo Clinic

    The purpose of this study is to assess abdominal wall contractions at rest, during maneuvers which activate the abdominal wall, and during simulated rectal ...

  9. Efficacy and Safety Study of CVT-301 In Parkinson's Disease Patients With OFF Episodes - Mayo Clinic

    About this study. This randomized, multicenter, placebo-controlled, double-blind study will evaluate the efficacy and safety of inhaled CVT 301 compared ...

  10. Trial to Understand Efficacy of Colesevelam in Diarrhea Predominant IBS Patients With Bile Acid Malabsorption - Mayo Clinic

    To compare with a randomized trial (n=15 per treatment group), effects of colesevelam and placebo treatment, on colonic transit, bowel functions, permeability ...