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  1. Dosing Regimen of Eculizumab Added to Conventional Treatment in Positive Crossmatch Deceased Donor Kidney Transplant - Mayo Clinic

    The purpose of this study is to test whether a dosing regimen of eculizumab in addition to standard posttransplant care in positive crossmatch deceased donor ...

  2. Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications - Mayo Clinic

    This study is designed to determine if point-of-care washing of allogeneic Leukocyte-Reduced Red Blood Cells reduces pulmonary complications when compared to ...

  3. A Study to Determine the Effectiveness and Safety of a New Nicotine Replacement Therapy - Mayo Clinic

    Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and ...

  4. A Study to Investigate the Safety and Effectiveness of SAPIEN 3 Transcatheter Heart Valve Implantation in Patients with a Failing Mitral Bioprosthetic Valve - Mayo Clinic

    The purpose of this study is to assess the safety and effectiveness of the SAPIEN 3 (Edwards Lifesciences, Irvine, California) transcatheter heart valve in ...

  5. Regenerative Biotherapeutic Development With Neonatally-derived Tissues - Mayo Clinic

    Its overall goal is to produce a Good Manufacturing Practice compliant, allogeneic therapeutic cell bank whereby therapeutic progenitor cells are obtained from ...

  6. Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants - Mayo Clinic

    The purpose of this registry is to establish genetically and clinically well-characterized cohorts of patients across hundreds of genetic variants associated ...

  7. Recurrent Cancer Clinical Trials - Mayo Clinic Research

    This phase Ib/II clinical trial studies the side effects and best dose of venetoclax and how well it works when given together with vincristine liposomal in ...

  8. The Effects of Aortic Valve Replacement on Sleep Disordered Breathing, Heart Rate Variability and Ventricular Ectopy Burden in Patients with Severe Aortic Stenosis - Mayo Clinic

    Our overall goal is to determine whether the AVR improves SDB where present and sleep profiles (including sleepiness symptoms, quality of life and hypoxia).

  9. Membership - Center for Multiple Sclerosis and Autoimmune Neurology - Mayo Clinic Research

    Faculty members conducting research through the Center for Multiple Sclerosis and Autoimmune Neurology at Mayo Clinic have wide-ranging expertise.

  10. A Study to Assess Neurological Worsening in Acute Ischemic Stroke Patients Using Cerebral Oximetry - Mayo Clinic

    The primary purpose of this study is to monitor patients with acute ischemic strokes who receive reperfusion therapies (tissue plasminogen activator, mechanical ...