1. July 28, 2023

    BEST model for cancer distress management

    Oncopsychology focuses on helping to manage the distress of serious conditions such as cancer in order to improve health outcomes. Mayo Clinic experts are taking gold standard methods and applying them in real-world, cl[...]

  2. March 20, 2018

    Patient-centered medical home membership affects ED admissions for behavioral health patients

    A study finds hospitalization costs for patients with behavioral health problems can be reduced through patient-centered medical home (PCMH) membership.

  3. March 20, 2018

    Increasing the happiness of health care workers

    Researchers found improvements in happiness, gratitude, stress levels and other domains in a study that looks at Stress Management and Resiliency Training (SMART) program for health care workers.

  4. Nov. 17, 2017

    Interventions for cancer caregivers indicate potential for quality of life improvement

    Caregivers for patients with advanced cancer can experience higher levels of energy and activity, adaptation, and spiritual well-being when administered a psychosocial intervention designed to improve quality of life (Q[...]

  5. Nov. 17, 2017

    Electroconvulsive therapy for adolescents: Make sure it's on the menu

    This review study finds electroconvulsive therapy (ECT) safe and effective for refractory adolescent psychiatric illness. For patients to benefit from ECT, however, psychiatrists must keep this therapy on the list of po[...]

  6. Nov. 17, 2017

    Update on new Mayo Clinic residential psychiatric treatment facility

    In spring 2018, Mayo Clinic will open a new residential psychiatric treatment facility in Rochester, Minnesota. The facility's medical and clinical directors answer questions referring physicians may have in this Q&[...]

  7. July 18, 2017

    Mayo Clinic to open residential psychiatric treatment facility

    The John E. Herman Home and Treatment Facility, in Collaboration with ClearView Communities, Mayo Clinic's new psychiatric residential treatment facility, will open in early 2018 in Rochester, Minnesota.

  8. July 15, 2017

    Deadliness of attempted suicide has been dramatically underestimated

    A Rochester Epidemiology Project-based study demonstrates that the year after a suicide attempt is crucial for potential recurrence, completed suicides are disproportionately male, and firearms far outstrip all other su[...]

  9. July 15, 2017

    Vigorous, supervised exercise enhances short-term smoking cessation among female smokers with depression

    This pilot study, conducted in a community setting, indicates that supervised exercise is effective, short-term, for women with depression who smoke. Long-term adherence was limited as participants' attendance at the ex[...]

  10. March 29, 2017

    Ketamine: Exploring continuation-phase treatment for depression

    Continuation-phase administration of ketamine at weekly intervals to patients with treatment-resistant depression who remitted during acute-phase ketamine treatment can extend the duration of depressive-symptom remissio[...]

  11. March 29, 2017

    Precision medicine and antidepressants

    Genetic variations in patients may contribute to the variability in effectiveness and adverse-effect toxicity profile of antidepressants. More-precise pharmacotherapeutic recommendations may improve treatment.

  12. March 28, 2017

    Acamprosate: Seeking individualized treatment for alcoholism

    Alcohol-dependent study participants with significantly elevated levels of anterior cingulate cortex glutamate (compared with controls) had reduced glutamate levels after four weeks of acamprosate treatment.

  13. Nov. 11, 2016

    Biobank research identifies bipolar-obesity link

    New research suggests a genetic link between body mass index (BMI) and the onset of bipolar disorder.

  14. Nov. 11, 2016

    Misconceptions hinder good psychiatric management of BPD

    General psychiatric management has proved as effective as dialectical-behavioral therapy for borderline personality disorder (BPD), but common misconceptions about the disease can prevent patients from receiving optimal[...]

  15. Nov. 11, 2016

    Epigenetic gene regulation may play role in psychiatric disorders

    Evidence increasingly suggests that epigenetic modifications, especially DNA methylation, are involved in schizophrenia and other psychiatric disorders.

  16. May 13, 2016

    Actigraphy superior to sleep logs in narcolepsy diagnosis

    Narcolepsy is misdiagnosed in as many as 50 percent of patients. Adding actigraphy to the evaluation leads to more accurate diagnosis and treatment.

  17. May 13, 2016

    Study to evaluate pharmacogenomic testing for adolescent depression

    A few studies suggest that therapy based on a genetic variation treatment algorithm may improve response in adults with depression. Mayo Clinic investigators are currently recruiting adolescents with depression for a si[...]

  18. May 13, 2016

    Intensive group therapy program improves pediatric mood disorders

    Mayo Clinic's Child and Adolescent Integrated Mood Program (CAIMP), a hospital-based, outpatient psychotherapy program, has been shown to reduce inpatient hospital readmissions by 80 percent for at least one year after [...]

  19. May 13, 2016

    App helps teens manage chronic pain

    A new app is designed to help teens overcome challenges of living with chronic pain.

  20. April 12, 2016

    Adults with nonparalytic forms of strabismus face increased risk of mental illness

    Research based on Rochester Epidemiology Project data indicates that adults with divergence insufficiency or small-angle hypertropia may be at increased risk of mental illness and its comorbidities.

  21. Feb. 16, 2016

    Study finds potential biomarkers for bipolar disorders

    The search for accurate methods for the identification and differentiation of mood disorders is ongoing. In a preliminary study, researchers identified six possible biomarkers for bipolar disorder.

  22. Feb. 13, 2016

    Collaborative care model significantly improves patient outcomes

    The Care of Mental, Physical and Substance Use Syndromes (COMPASS) model aims to improve the quality, experience and affordability of care for adults with depression and chronic comorbidities. Successful in studies, it [...]

  23. Feb. 13, 2016

    Long-term adjunctive benzodiazepines may not improve outcomes in bipolar disorder

    Although benzodiazepines can be helpful in acute settings as adjuncts to core mood stabilizers, a new study fails to find evidence to support their long-term use in patients with bipolar disorder.

  24. Nov. 10, 2015

    Gastric bypass-associated AUD: Progression and clinical implications

    According to a new study, as many as 10 to 15 percent of patients undergoing Roux-en-Y gastric bypass develop alcohol use disorder (AUD) by three years post-surgery. Mayo Clinic clinicians now recommend abstinence or se[...]

  25. Nov. 10, 2015

    Tobacco cessation interventions target pregnant Alaska Native women

    Alaska Native women have high rates of tobacco use before, during and after pregnancy. Interventions to reduce smoking in this population have not been successful to date, but a new anti-smoking campaign that targets en[...]

  26. Nov. 10, 2015

    Exposure therapy effective for pediatric anxiety and OCD

    Although not widely available, parent-coached exposure therapy may provide greater improvement in less time than does cognitive behavioral therapy for children with anxiety disorders and obsessive-compulsive disorder (O[...]

  27. Aug. 07, 2015

    Extended ADHD age criterion captures more minority, low-income and inattentive children

    A new study finds that the expanded age-of-onset criterion for ADHD increases prevalence by nearly 3.5 percent. The increase is greatest among children with inattentive symptoms and those from low-income and minority fa[...]

  28. Aug. 07, 2015

    Mayo provides integrated care for people with gender dysphoria

    Transgender people experience significant health care discrimination. Mayo Clinic offers integrated medical and psychosocial interventions to help optimize quality of life for this marginalized and vulnerable population[...]

  29. Aug. 07, 2015

    Lamotrigine normalizes NAA in bipolar depression

    A new study found that lamotrigine increased lower than normal N-acetylaspartate (NAA) in patients with bipolar depression. Although the results showed a brain change only, larger studies may find a correlation with imp[...]

  30. May 14, 2015

    Genes may compound effects of depression on bone loss

    A functional polymorphism of the serotonin transporter promoter gene produces two main alleles, short (s) and long (l). New research shows that the s allele may be associated with increased bo[...]

  31. May 12, 2015

    MCI interventions aid patients and caregivers

    Mayo Clinic's 10-day Healthy Action to Benefit Independence and Thinking (HABIT) program uses memory compensation training and other interventions to help delay the progression of mild cognitive impairment and relieve c[...]

  32. Feb. 10, 2015

    Adult ADHD presents diagnostic and therapeutic challenges

    ADHD symptoms in adults include attention issues, such as difficulty with planning, follow-through, organization and time management. Treatment plans should identify patients' strengths and weaknesses, assess for residu[...]

  33. Feb. 10, 2015

    Expanding the collaborative care model

    Many trials have demonstrated that collaborative care for depression is more effective than usual care in various settings. Mayo specialists also are working to develop collaborative care programs for patients with anxi[...]

  34. Dec. 04, 2014

    Searching beyond the genome: SSRI pharmacogenomics

    Mayo researchers have performed the first genome-wide association study for plasma concentrations of escitalopram and its metabolites in patients with major depressive disorder who were treated with the medication.

  35. Dec. 04, 2014

    Implementing drug-gene rules

    In a key innovation developed by a Mayo task force, if a patient is at risk of a drug-gene interaction, a warning appears when the clinician enters the prescribed medication into the patient's EMR.

  36. Dec. 04, 2014

    Right drug, right dose, right patient

    A new Mayo Clinic study explores whether pharmacogenomic testing should be part of regular clinical practice — before antidepressant therapy starts — to minimize the number of unsuccessful medication trials [...]

  37. Sept. 04, 2014

    QOL videoconferencing program may ease caregiver burden

    Given the proven ability of a structured, multidisciplinary intervention to improve quality of life (QOL) for patients with advanced-stage cancer, Mayo researchers have designed a similar program for cancer caregivers.

  38. Sept. 04, 2014

    Varenicline may be safe and effective for smoking cessation in bipolar disorder

    Patients with bipolar disorder who smoke have lower response rates to mood-stabilizing drugs than nonsmokers do. A small study suggests varenicline may be a feasible option for reducing tobacco use in these patients.

  39. Sept. 04, 2014

    Ketamine research focuses on mechanisms of action and biomarker development

    In studies, subanesthesia doses of ketamine rapidly improve mood and suicidal ideation in some patients with depressive disorders. Research is now underway to determine how the drug works and which patients are likely t[...]

  40. Sept. 04, 2014

    Environmental and psychosocial interventions help manage dementia behavior

    By focusing on environmental, psychosocial and organic factors contributing to challenging behavior, Mayo Clinic's Dementia-Behavioral Assessment and Response Team (D-BART) is changing the standard of care for people wi[...]

  41. June 05, 2014

    CONNECT trial tests effectiveness, feasibility of remote TBI care

    A new study aims to determine the effectiveness of a partnership between Mayo Clinic and community providers in managing the post-acute care of traumatic brain injury (TBI) patients.

  42. June 05, 2014

    Primary progressive apraxia of speech a distinct neurodegenerative syndrome

    A new study shows that primary progressive apraxia of speech, a disorder of speech motor planning or programming, is distinct from aphasia and dysarthria and can be the sole presenting sign of neurodegenerative disease.[...]

  43. June 05, 2014

    New trial evaluates rTMS for adolescent depression

    Repetitive transcranial magnetic stimulation (rTMS) may be a safe and effective option for adolescents with major depressive disorder who don't respond to pharmacotherapy and psychotherapy.

  44. March 06, 2014

    Mayo Clinic Depression Center offers innovative, integrated care

    To meet the growing need for effective care, the Mayo Clinic Depression Center offers four innovative, evidence-based programs for people with bipolar disorder or major depression.

  45. March 06, 2014

    Mayo unveils destination medical center plan

    In spring 2013, Mayo Clinic announced a 20-year, $5.6 billion economic development plan aimed at making Mayo Clinic and, by extension, Rochester, Minn., one of the leading medical destinations in the world.

  46. March 06, 2014

    Pain Rehabilitation Center improves pain and function without opioids

    Mayo Clinic's adult and pediatric pain rehabilitation program treats more than 700 patients annually. Its highly skilled and experienced programs and specialists provide safe, effective tapering of low- and high-dose op[...]

  47. Nov. 15, 2013

    DSM-5 redefines hypochondriasis

    In the newly approved Diagnostic and Statistical Manual of Mental Disorders (DSM-5) updated edition, hypochondriasis and several related conditions have been replaced by two new, empirically derived concepts: somatic sy[...]