Pediatrics

Below are current clinical trials.

Filter this list of studies by location, status and more.

1. Hypoplastic Left Heart Syndrome: Validating Functional Parameters and Novel Echocardiographic Imaging Strategies for Evaluation of Functionally Single Right Ventricular Performance using Previously Recorded Studies

   Rochester, Minn.

   The purpose of this study is to validate novel echocardiographic parameters and algorithms to quantitatively evaluate right ventricular function in patients with Hypoplastic Left Heart Syndrome (HLHS) by applying these methods to previously acquired echocardiographic examinations. 

2. A Study to Establish a Pediatric Spine Registry

   Rochester, Minn., Minneapolis, Minn.

   The purpose of this study is to collect data about patients with chest wall and spinal deformities to develop a multicenter registry.  This will speed the pace of medical advancement and treatment recommendations for these conditions. 

3. Happigenius Social-Emotional Learning Curriculum in Rochester Public Schools

   Rochester, Minn.

   The purpose of this study is to test the effectiveness of HappiGenius curriculum in 3rd grade students attending elementary school in the Rochester Public Schools system (Rochester, MN). Convenience samples are selected from students in classrooms receiving the HappiGenius curriculum in their normal school curriculum and students in classrooms that have opted not to have HappiGenius in their classroom this term. For the study, questionnaires will be administered at the start and conclusion of HappiGenius lessons to determine whether HappiGenius curriculum delivers the core competencies of improved attention, positive affect, self-awareness, sociality, and self-kindness.

4. Patient-Specific Induced Pluripotent Stem Cell Models for Heritable Channelopathies and Cardiomyopathies

   Rochester, Minn.

   The purpose of this study is to derive and characterize patient-specific disease models for sudden death-predisposing heritable channelopathies and cardiomyopathies using iPS-cell technology.  It is hoped that the molecular, cellular, and electrophysiological phenotypes of these in-vitro disease models will further elucidate the pathophysiologic mechanisms underlying these sudden death-associated conditions.

5. A Study Measuring the Effectiveness of Simulated Preparation for Commonly Encountered Emotional, Cultural and Medical Difficulties in Global Health Experiences

   Rochester, Minn.

   The purpose of this study is to determine if SUGAR simulated training is effective in preparing individuals for the emotional, cultural and medical difficulties often encountered during participation in global health experiences (GHE). More specifically, we will be comparing the responses and effectiveness between participants of various specialty backgrounds and at various stages of training.

6. A Study of the Effects of Preterm Birth on Lung Disease and Innate Immunity Later in Life

   Rochester, Minn.

   The primary purpose of this study is to investigate the cytokine responses of blood ILC2s from preterm children by collecting peripheral blood at age 5-10 years from children born either preterm or at term, and to analyze the functions of their circulating ILC2s in vitro.

    

7. To Assess The Efficacy, Safety, And Tolerability Of INCB000928 In Participants With Fibrodysplasia Ossificans Progressiva

   Rochester, Minn.

   This Phase 2, Randomized, Double-Blind, Placebo-Controlled Study is intended to evaluate the Efficacy, Safety, and Tolerability and PK of INCB000928 administered to participants with a clinical diagnosis of fibrodysplasia ossificans progressiva (FOP).

8. Benevolent Tumor Tissue Repository Fighting for the Legacy of our Young

   Rochester, Minn.

   The aim of this study is to create a patient and patient-advocate catalyzed tumor bank for the retrieval, processing, analysis, and maintenance of pre-treatment, post-treatment and (when available) post-mortem soft tissue sarcoma (STS) tissue and tissue data with an emphasis on STSs occurring in younger patients (YP-STS). This resource-platform will be named Project BTTRFLY (Benevolent Tumor Tissue Repository Fighting for the Legacy of our Young).  

9. Associated Anomalies with Right and Left Cusp Fusion Versus Right and Non-Coronary Cusp Fusion

   Rochester, Minn.

   The goal of this study is to determine whether significant differences exist in the prevalence of associated cardiac anomalies between right/left and right / non-coronary cusp fusion in bicuspid aortic valve.

10. A Study to Evaluate Analgesic Use and Duration for Pediatric Long Bone Fractures

    Rochester, Minn.

    The purpose of this study is to develop an evidenced-based guideline for pediatric opioid prescribing guideline from the emergency department for long bone fractures to more closely tailor pain management to abuse potential.